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- 详细信息
- 文献和实验
- 技术资料
- 克隆性:
多克隆
- 抗体英文名:
EDEM1 Antibody (ER degradation-enhancing alpha-mannosidase-like protein 1 )
- 规格:
100 ug
产品名称:EDEM1抗体|EDEM1 Antibody (ER degradation-enhancing alpha-mannosidase-like protein 1 )
【产品形式】:艾美捷为您提供的EDEM1抗体产品为无色溶液形式,含有100 ug抗体.该产品浓度为0.5 mg/ml,溶解于包含有0.01 % BSA, 0.01 % 硫柳汞和50 % 甘油的PBS(pH 7.2)缓冲液中.请在收到该EDEM1抗体产品后,将其置于-20 °C冷冻保存,建议分装使用以避免反复冻融.
【背景资料】:EDEM1 belongs to the glycosyl hydrolase 47 family. It extracts misfolded glycoproteins, but not glycoproteins undergoing productive folding, from the calnexin cycle. It is directly involved in endoplasmic reticulum-associated degradation (ERAD) and targets misfolded glycoproteins for degradation in an N-glycan-dependent manner.
BioVision的公司总部在美丽的旧金山湾地区,它是全球生命科学公司的领导者.BioVision在开发和研究细胞凋亡检测分析、代谢检测方面具有 卓越的影响力.包括检测各种检测分析试剂盒、相关特色抗体、重组蛋白及细胞因子和酶等多种产品,以及其他创新的研究工具.其产品覆盖细胞凋亡研究、能量代 谢、细胞/组织蛋白提取、氧化应激与损伤、代谢与肥胖症、细胞增殖与毒性、信号转导、干细胞研究等领域.作为多家知名品牌的中国总代理以及中国区域代理, 艾美捷与BioVision一起为研究者们提供最好、最新的细胞生物学研究工具而不断扩大产品及服务质量.
点击:EDEM1抗体,查看更详细产品说明,更多应用、储存、价格、货期等信息请致电400-6800-868垂询BioVision中国区域授权总代理艾美捷科技有限公司。
关键词:EDEM1,EDEM1抗体
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文献和实验CFTR Expression and ER-Associated Degradation in Yeast
chaperones may play a pivotal role in this process, as they associate with CFTR in the ER and are released upon protein maturation or degradation (6 -8 ). In accordance with this hypothesis, molecular chaperones are known to aid in protein targeting
Reticulocyte Lysate as a Model System to Study Endoplasmic Reticulum Membrane Protein Degradation
isolated in native ER membranes which, when incubated in RRL lacking exogenous hemin, are degraded in an ATP-dependent manner by the ubiquitin-proteasome pathway. Because the newly translated protein is the only source of radiolabel, degradation
protein quality control and degradation system required for the elimination of the substrate variety. Protein quality control of the ER and subsequent degradation are evolutionarily highly conserved from yeast to human. The yeast Saccharomyces cerevisiae
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