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- 详细信息
- 技术资料
- 克隆性:
多克隆
- 抗体英文名:
LC3 (APG8) antibody (Clone 166AT1234) (MAP1LC3A; Microtubule-associated proteins 1A/1B light chain 3A; Autophagy-related protein LC3 A; Autophagy-related ubiquitin-like modifier LC
- 规格:
100 ul
产品名称:LC3 (APG8)抗体(克隆号166AT1234)|LC3 (APG8) antibody (Clone 166AT1234) (MAP1LC3A; Microtubule-associated proteins 1A/1B light chain 3A; Autophagy-related protein LC3 A; Autophagy-related ubiquitin-like modifier LC
【产品形式】:艾美捷为您提供的LC3 (APG8)抗体(克隆号166AT1234)产品为无色溶液形式,含有100 ug抗体.该产品浓度为1 mg/ml,溶解于包含有0.09% (W/V) NaN3的PBS缓冲液中.请在收到该LC3 (APG8)抗体(克隆号166AT1234)产品后,将其置于-20 °C冷冻保存,建议分装使用以避免反复冻融.
【背景资料】:Autophagy is an alternative process of proteasomal degradation for some long-lived proteins or organelles. Alterations in the autophagic-lysosomal compartment have been linked to neuronal death in many neurodegenerative disorders as well as in transmissible neuronal pathologies (prion diseases). Genetic studies in yeast have shown that Autophagy-defective Gene-8 (Atg-8) represents a specific marker for autophagy. Among the four families of mammalian Atg8-related proteins only LC3 (Microtubule-associated Protein1 Light Chain 3) is expressed at sufficient high levels and efficiently recruited to autophagic vesicles in cells and tissues. During autophagy the cytoplasmic form, LC3-I is processed and recruited to autophagosomes, where LC3-II is generated by site specific proteolysis near to the C-terminus. Autophagic vacuoles have been also reported frequently in cardiomyopathies or muscle cells exposed to different experimental settings.
BioVision的公司总部在美丽的旧金山湾地区,它是全球生命科学公司的领导者.BioVision在开发和研究细胞凋亡检测分析、代谢检测方面具有 卓越的影响力.包括检测各种检测分析试剂盒、相关特色抗体、重组蛋白及细胞因子和酶等多种产品,以及其他创新的研究工具.其产品覆盖细胞凋亡研究、能量代 谢、细胞/组织蛋白提取、氧化应激与损伤、代谢与肥胖症、细胞增殖与毒性、信号转导、干细胞研究等领域.作为多家知名品牌的中国总代理以及中国区域代理, 艾美捷与BioVision一起为研究者们提供最好、最新的细胞生物学研究工具而不断扩大产品及服务质量.
点击:LC3 (APG8)抗体(克隆号166AT1234),查看更详细产品说明,更多应用、储存、价格、货期等信息请致电400-6800-868垂询BioVision中国区域授权总代理艾美捷科技有限公司。
关键词:LC3 ,LC3 (APG8)抗体(克隆号166AT1234)
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