【产品形式】:艾美捷为您提供的SDF-1alpha抗体产品为100 ug 无色溶液,其浓度为0.5 mg/ml,溶解于包含有30%甘油和0.01硫柳汞的PBS (pH 7.2)缓冲液中.请将该SDF-1alpha抗体产品置于-20 ℃冷冻保存,建议分装使用以避免反复冻融.
【背景资料】:SDF-1α (stromal cell-derived factor-α), also known as pre-B-cell growth-stimulating factor (PBSF), is a 70-amino acid CXC chemokine originally cloned from a bone marrow stromal cell line. Targeted deletion of SDF-1 gene resulted in defects of B-cell lymphopoiesis and bone marrow myelopoiesis. SDF-1 has been shown to be chemotactic for lymphocytes. In addition, SDF-1 was recently reported to be a ligand for CXCR4 (LESTR/fusin), a co-receptor for HIV-1 entry into T cells. SDF-1 binding to CXCR4 inhibits HIV-1 entry.