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- 详细信息
- 文献和实验
- 技术资料
- 克隆性:
多克隆
- 抗体英文名:
TFAM Antibody,Transcription factor A,MtTF1,TCF6,TCF6L2,mtTFA
- 规格:
100 ug
产品名称:TFAM抗体|TFAM Antibody,Transcription factor A,MtTF1,TCF6,TCF6L2,mtTFA
【产品形式】:艾美捷为您提供的TFAM抗体产品为100 ug 无色溶液,其浓度为0.5 mg/ml,溶解于包含有30%甘油, 0.5% BSA和0.01%硫柳汞的PBS缓冲液中.请将该TFAM抗体产品置于-20 ℃冷冻保存,建议分装使用以避免反复冻融.
【背景资料】:Transcription factor A mitochondria (TFAM) is an important activator of mitochondrial DNA transcription and replication. Studies in mice have shown that TFAM is required to regulate the mitochondrial genome copy number and is important for embryonic development. TFAM has been associated with mitochondrial disorder which includes ocular myopathy and muscular wasting in humans. Kearns-Sayre syndrome was shown in mouse model when expression of the gene was eliminated by targeted disruption in heart and muscle cells.
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点击:TFAM抗体,查看更详细产品说明,更多应用、储存、价格、货期等信息请致电400-6800-868垂询BioVision中国区域授权总代理艾美捷科技有限公司。
关键词:TFAM,TFAM抗体
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文献和实验Methods for Assessing Binding of Mitochondrial Transcription Factor A (TFAM) to DNA
It is now recognized that mammalian mitochondrial DNA forms a higher structure called the nucleoid, corresponding to the nucleosome of nuclear DNA. Mitochondrial transcription factor A (TFAM), which was cloned as a transcription factor
Assays for Transcription Factor Activity
Most transcription activator proteins have three important features that can be probed at the molecular level: They bind to specific sequences near promoters, they can be interconverted between active and inactive forms by covalent or noncovalent
Assaying Transcription Factor Stability
Similar to the activities of transcription factors (TFs) in other eukaryotes, activities of many plant TFs are determined via regulated proteolysis by the ubiquitin/26S proteasome system. Thus, to fully understand the function of a TF
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