PIM1 Antibody,PIM,PIM1,PIM-1,Proviral Integration Site 1
规格:
100 ug
产品名称:PIM1抗体|PIM1 Antibody,PIM,PIM1,PIM-1,Proviral Integration Site 1
【产品形式】:艾美捷为您提供的PIM1抗体产品为100 ug 无色溶液,其浓度为0.5 mg/ml,溶解于包含有30%甘油, 0.5 % BSA和0.01%硫柳汞的PBS, pH 7.2)缓冲液中.请将该PIM1抗体产品置于-20 ℃冷冻保存,建议分装使用以避免反复冻融.
【背景资料】:The proto-oncogene Pim1 belongs to a family of serine/threonine protein kinases that are highly conserved through evolution in multicellular organisms. Pim1 is involved in the control of cytokine-mediated cell proliferation, differentiation and survival of lymphoid and myeloid cells as well as others. Expression of Pim1 can be stimulated by a variety of growth factors and is regulated at four different levels: transcriptional, post-transcriptional, translational and post-translational. Recently, Pim1 has been shown to enhance the activities of p100, c-Myb and Cdc 25a and in part this might explain reported effects of Pim1 on mitogenesis.