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- 详细信息
- 文献和实验
- 技术资料
- 克隆性:
多克隆
- 抗体英文名:
Wnt-1 Antibody,wnt1,wnt 1,wnt-1,INT 1,INT1,wingless type MMTV integration site family member 1
- 规格:
100 ug
产品名称:Wnt-1抗体 |Wnt-1 Antibody,wnt1,wnt 1,wnt-1,INT 1,INT1,wingless type MMTV integration site family member 1
【产品形式】:艾美捷为您提供的Wnt-1抗体 产品为100 ug 无色溶液,其浓度为0.5 mg/ml,溶解于包含有30%甘油, 0.5% BSA和0.01%硫柳汞 的PBS缓冲液中.请将该Wnt-1抗体 产品置于-20 ℃冷冻保存,建议分装使用以避免反复冻融.
【背景资料】:Wnt gene family members, including Wnt-1 through Wnt-10, play a key role in regulating cellular growth and differentiation. Wnt-1 is a cysteine-rich, secreted glycoprotein that associates with cell membranes and likely functions as a key regulator of cellular adhesion. Wnt-1, which is essential for normal development of the embryonic nervous system, contributes to hyperplasia and tumorigenic progression when improperly expressed in mammary tissue. Wnt-3 is also involved in tumorigenesis and Wnt-2 and Wnt-4 may be associated with abnormal proliferation in human breast tissue. Wnt-1, Wnt-3 and Wnt-10b have been implicated along with FGF-3 in the development of mouse mammary tumor virus induced mouse mammary carcinomas.
BioVision的公司总部在美丽的旧金山湾地区,它是全球生命科学公司的领导者.BioVision在开发和研究细胞凋亡检测分析、代谢检测方面具有 卓越的影响力.包括检测各种检测分析试剂盒、相关特色抗体、重组蛋白及细胞因子和酶等多种产品,以及其他创新的研究工具.其产品覆盖细胞凋亡研究、能量代 谢、细胞/组织蛋白提取、氧化应激与损伤、代谢与肥胖症、细胞增殖与毒性、信号转导、干细胞研究等领域.作为多家知名品牌的中国总代理以及中国区域代理, 艾美捷与BioVision一起为研究者们提供最好、最新的细胞生物学研究工具而不断扩大产品及服务质量.
点击:Wnt-1抗体 ,查看更详细产品说明,更多应用、储存、价格、货期等信息请致电400-6800-868垂询BioVision中国区域授权总代理艾美捷科技有限公司。
关键词:Wnt,Wnt-1抗体
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文献和实验Systemor equivalent). 4. Nitrocellulose or polyvinyl difluoride (PVDF) membrane. 5. Wnt3A antibody (available from R&D Systems, Minneapolis,MN). 6. Appropriate conjugated secondary antibody for detection. 2.4.2. b-Catenin Stabilization
v468.chapter 1 经典 Wnt/b-Catenin 信号通路 (英文完整版)
(originally named Int1), was identified in 1982 as a geneinappropriately activated by integration of the Mouse MammaryTumor Virus in virally induced breast tumors (1) . This establishedthe first link between mis-expression of Wnt genes andcancer (branding Wnt
v468.Chapter 3 分泌型跨膜相关蛋白提纯及Wnt抑制活性
)-type, cysteine-rich domain (CRD) that serves as a bindingsite for Wnts as well as other sFRPs and Fzds (1) . Much evidenceindicates that sFRPs can function as Wnt antagonists, presumablyby sequestering Wnts or interacting with Fzds to disruptligand
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