Stat6 Antibody,Signal transducer and activator of transcription6,STAT6B,STAT6C,D12S1644,IL-4-STAT,interleukin 4 induced STAT
规格:
100 ug
产品名称:Stat6抗体 |Stat6 Antibody,Signal transducer and activator of transcription6,STAT6B,STAT6C,D12S1644,IL-4-STAT,interleukin 4 induced STAT
【产品形式】:艾美捷为您提供的Stat6抗体 产品为100 ug 无色溶液,其浓度为0.5 mg/ml,溶解于包含有30%甘油, 0.5% BSA和0.01%硫柳汞的PBS缓冲液中.请将该Stat6抗体 产品置于-20 ℃冷冻保存,建议分装使用以避免反复冻融.
【背景资料】:Membrane receptor signaling by various ligands induces activation of Jak kinases which then leads to tyrosine phosphorylation of the various Stat transcription factors. Stat1 and Stat2 are induced by IFN-α and form a heterodimer which is part of the ISGF3 transcription factor complex. Although early reports indicate Stat3 activation by EGF and IL-6, it has been shown that Stat3β appears to be activated by both while Stat3α is activated by EGF, but not by IL-6. Highest expression of Stat4 is seen in testis and myeloid cells. IL-12 has been identified as an activator of Stat4. Stat5 is activated by prolactin and by IL-3. Stat6 is involved in IL-4 activated signaling pathways.