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- 详细信息
- 文献和实验
- 技术资料
- 克隆性:
多克隆
- 抗体英文名:
Stat6 Antibody,Signal transducer and activator of transcription6,STAT6B,STAT6C,D12S1644,IL-4-STAT,interleukin 4 induced STAT
- 规格:
100 ug
产品名称:Stat6抗体 |Stat6 Antibody,Signal transducer and activator of transcription6,STAT6B,STAT6C,D12S1644,IL-4-STAT,interleukin 4 induced STAT
【产品形式】:艾美捷为您提供的Stat6抗体 产品为100 ug 无色溶液,其浓度为0.5 mg/ml,溶解于包含有30%甘油, 0.5% BSA和0.01%硫柳汞的PBS缓冲液中.请将该Stat6抗体 产品置于-20 ℃冷冻保存,建议分装使用以避免反复冻融.
【背景资料】:Membrane receptor signaling by various ligands induces activation of Jak kinases which then leads to tyrosine phosphorylation of the various Stat transcription factors. Stat1 and Stat2 are induced by IFN-α and form a heterodimer which is part of the ISGF3 transcription factor complex. Although early reports indicate Stat3 activation by EGF and IL-6, it has been shown that Stat3β appears to be activated by both while Stat3α is activated by EGF, but not by IL-6. Highest expression of Stat4 is seen in testis and myeloid cells. IL-12 has been identified as an activator of Stat4. Stat5 is activated by prolactin and by IL-3. Stat6 is involved in IL-4 activated signaling pathways.
BioVision的公司总部在美丽的旧金山湾地区,它是全球生命科学公司的领导者.BioVision在开发和研究细胞凋亡检测分析、代谢检测方面具有 卓越的影响力.包括检测各种检测分析试剂盒、相关特色抗体、重组蛋白及细胞因子和酶等多种产品,以及其他创新的研究工具.其产品覆盖细胞凋亡研究、能量代 谢、细胞/组织蛋白提取、氧化应激与损伤、代谢与肥胖症、细胞增殖与毒性、信号转导、干细胞研究等领域.作为多家知名品牌的中国总代理以及中国区域代理, 艾美捷与BioVision一起为研究者们提供最好、最新的细胞生物学研究工具而不断扩大产品及服务质量.
点击:Stat6抗体 ,查看更详细产品说明,更多应用、储存、价格、货期等信息请致电400-6800-868垂询BioVision中国区域授权总代理艾美捷科技有限公司。
关键词:Stat,Stat6抗体
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文献和实验-I-receptor protein and a JAK3 interaction with γ c. IL-21-mediated signalling leads to the activation of mainly signal transducer and activator of transcription 1 (STAT1) and STAT3, whereas IL-7-mediated signalling and IL-15-mediated signalling mainly
activation motif; JAK, Janus kinase; NFκB, nuclear factor κB; PKB, protein kinase B; PLC, phospholipase C; SIGIRR, single Ig IL-1-related receptor; sIL-1RAcP, soluble IL-1 receptor accessory protein; sST2, soluble ST2; STAT3, signal transducer and activator
【进展|热点】PD-1信号通过上调BATF抑制HIV特异性CD8阳性T细胞的功能
,探寻到3个特异性表达上调的转录因子:BATF, signal transducer and activator of transcription-1 (STAT1)和interferon regulatory factor-9 (IRF9)。采用构建BATF过表达载体转染T细胞,并应用siRNA策略考察BATF蛋白对T细胞分泌相应细胞因子能力的影响,深入探讨了BATF分子的生物学功能及其与HIV特异性T细胞活性之间的关系。文章认为,PD-1介导的抑制性信号除了可以降低TCR传导的特异性刺激信号
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