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- 详细信息
- 文献和实验
- 技术资料
- 克隆性:
多克隆
- 抗体英文名:
Cadherin Antibody,P-cadherin,N-Cadherin,E-Cadherin,K-Cadherin,M-jadherin,R-Cadherin
- 规格:
100 ug
产品名称:Cadherin抗体|Cadherin Antibody,P-cadherin,N-Cadherin,E-Cadherin,K-Cadherin,M-jadherin,R-Cadherin
【产品形式】:艾美捷为您提供的Cadherin抗体产品为100 ug 无色溶液,其浓度为0.5 mg/ml,溶解于包含有30%甘油, 0.5% BSA, 0.01%硫柳汞的PBS (pH 7.2)缓冲液中.请将该Cadherin抗体产品置于-20 ℃冷冻保存,建议分装使用以避免反复冻融.
【背景资料】:Cadherins comprise a family of Ca-dependent adhesion molecules that function to mediate cell-cell binding critical to the maintenance of tissue structure and morphogenesis. Cadherins consist of large extracellular domains characterized by a series of five homologous NH2 terminal repeats. The most distal of cadherins is though to be responsible for binding specificity, transmembrane domains and carboxy terminal domains. The relative short intracellular domains interact with a variety of cytoplasmic proteins, such as β-catenin, to regulate cadherin function.
BioVision的公司总部在美丽的旧金山湾地区,它是全球生命科学公司的领导者.BioVision在开发和研究细胞凋亡检测分析、代谢检测方面具有 卓越的影响力.包括检测各种检测分析试剂盒、相关特色抗体、重组蛋白及细胞因子和酶等多种产品,以及其他创新的研究工具.其产品覆盖细胞凋亡研究、能量代 谢、细胞/组织蛋白提取、氧化应激与损伤、代谢与肥胖症、细胞增殖与毒性、信号转导、干细胞研究等领域.作为多家知名品牌的中国总代理以及中国区域代理, 艾美捷与BioVision一起为研究者们提供最好、最新的细胞生物学研究工具而不断扩大产品及服务质量.
点击:Cadherin抗体,查看更详细产品说明,更多应用、储存、价格、货期等信息请致电400-6800-868垂询BioVision中国区域授权总代理艾美捷科技有限公司。
关键词:Cadherin,Cadherin抗体
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文献和实验与配体的结合,发挥细胞粘附功能。 图2-6 Cadherin分子的结构模式图 注:图中黑区部分显示Cadherin分子内重复结构域;LDRE及DXNDN为重复序列。 (二)Cadherin家族的组成和分布 目前已知Cadherin家族共有3个成员:E-Cadherin、N-Cadherin和P-Cadherin。E-Cadherin也被称作Uvomorulin、L-CAM或Cell-CAM120/80。不同
Cadherin-Mediated Cell-Cell Interactions
Cadherins constitute a family of transmembrane glycoproteins (Table 1 ) that mediate cell-cell adhesion by their ability to self-associate (1 –4 ). For example, E-cadherin binds only to E-cadherin and not to N-cadherin. The homotypic
Tracking the Transport of E-Cadherin to and From the Plasma Membrane
, it is also a key occurrence in many diseases, including cancers of epithelial origin E-cadherin is a central component of adherens junctions (AJs), which act as structural and signaling hubs in epithelial cells that oppose EMT. The loss of E-cadherin
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