SODD抗体|SODD Antibody，silencer

产品名称：SODD抗体|SODD Antibody，silencer of death domains，BAG family molecular chaperone regulator 4； BAG-4； Bcl-2-associated athanogene 4； Silencer of death domains

【产品形式】：艾美捷为您提供的SODD抗体产品为100 ug 无色溶液，其浓度为0.5 mg/ml，溶解于包含有50%甘油， 1% BSA， 0.02%硫柳汞的PBS （pH 7.2）缓冲液中.请将该SODD抗体产品置于-20 ℃冷冻保存，建议分装使用以避免反复冻融.

【背景资料】：Apoptosis is induced by certain cytokines including TNF and Fas ligand of the TNF family through their death domain containing receptors， TNF-R1 and Fas. Several novel death receptors including DR3， DR4， DR5， and DR6 were recently identified. Cell death signal is transduced by death domain containing adapter molecules through the interaction with death domain of these death receptors. A novel TNF-R1 interacting protein was recently identified and designated SODD for silencer of death domain. SODD associates with the death domain of TNF-R1 and prevents constitutive activation of TNF-R1 signaling. TNF treatment releases SODD and permits adapter molecules such as TRADD recruiting to the active TNF-R1 complex， which activates TNF signaling pathways. SODD also interacts with DR3. SODD is ubiquitously expressed in human tissues and cell lines.

BioVision的公司总部在美丽的旧金山湾地区，它是全球生命科学公司的领导者.BioVision在开发和研究细胞凋亡检测分析、代谢检测方面具有 卓越的影响力.包括检测各种检测分析试剂盒、相关特色抗体、重组蛋白及细胞因子和酶等多种产品，以及其他创新的研究工具.其产品覆盖细胞凋亡研究、能量代 谢、细胞/组织蛋白提取、氧化应激与损伤、代谢与肥胖症、细胞增殖与毒性、信号转导、干细胞研究等领域.作为多家知名品牌的中国总代理以及中国区域代理， 艾美捷与BioVision一起为研究者们提供最好、最新的细胞生物学研究工具而不断扩大产品及服务质量.

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关键词：SODD，SODD抗体