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- 详细信息
- 文献和实验
- 技术资料
- 克隆性:
多克隆
- 抗体英文名:
AMPKα Antibody,Protein kinase AMP-activated alpha-1 catalytic subunit,AMPK alpha-1 chain,
- 规格:
100 ug
产品名称:AMPKα抗体|AMPKα Antibody,Protein kinase AMP-activated alpha-1 catalytic subunit,AMPK alpha-1 chain,
【产品形式】:艾美捷为您提供的AMPKα抗体产品为100 ug 无色溶液,其浓度为0.25 mg/ml,溶解于包含有0.09% (W/V) 叠氮钠的PBS缓冲液中.请将该AMPKα抗体产品置于-20 ℃冷冻保存,建议分装使用以避免反复冻融.
【背景资料】:AMPKα (PRKAA1) belongs to the ser/thr protein kinase family. It is the catalytic subunit of the 5’-prime-AMP-activated protein kinase (AMPK). AMPK is a cellular energy sensor conserved in all eukaryotic cells. The kinase activity of AMPK is activated by the stimuli that increase the cellular AMP/ATP ratio. AMPK regulates the activities of a number of key metabolic enzymes through phosphorylation. It protects cells from stresses that cause ATP depletion by switching off ATP-consuming biosynthetic pathways.
BioVision的公司总部在美丽的旧金山湾地区,它是全球生命科学公司的领导者.BioVision在开发和研究细胞凋亡检测分析、代谢检测方面具有 卓越的影响力.包括检测各种检测分析试剂盒、相关特色抗体、重组蛋白及细胞因子和酶等多种产品,以及其他创新的研究工具.其产品覆盖细胞凋亡研究、能量代 谢、细胞/组织蛋白提取、氧化应激与损伤、代谢与肥胖症、细胞增殖与毒性、信号转导、干细胞研究等领域.作为多家知名品牌的中国总代理以及中国区域代理, 艾美捷与BioVision一起为研究者们提供最好、最新的细胞生物学研究工具而不断扩大产品及服务质量.
点击:AMPKα抗体,查看更详细产品说明,更多应用、储存、价格、货期等信息请致电400-6800-868垂询BioVision中国区域授权总代理艾美捷科技有限公司。
关键词:AMPK,AMPKα抗体
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文献和实验(3 ). PKA is composed of two catalytic (C) and two regulatory (R) subunits and has type I and type II isozymes, with different R subunits, termed RI and RII, interacting with an identical C subunit (1 ). Thus far, four isoforms of R subunits, RIα, RIβ, RIIα
又称依赖于cAMP的蛋白激酶A (cyclic-AMP dependent protein kinase A),是一种结构最简单、生化特性最清楚的蛋白激酶。 PKA全酶分子是由四个亚基组成的四聚体, 其中两个是调节亚基(regulatory subunit, 简称R 亚基),另两个是催化亚基(catalytic subunit, 简称 C 亚基)。R亚基的相对分子质量为49~55kDa, C亚基的相对分子质量为40kDa,总相对分子质量约为180kDa;全酶没有
DNA-Dependent Protein Kinase in Apoptosis
target proteins, one of which is the catalytic subunit of DNA-dependent protein kinase (DNA-PKcs). The antiapoptotic factor Bcl-xL can sequester cytochrome C and inhibit the formation of the caspase-9-Apaf-1 complex effectively blocking apoptosis
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