Atg7 多克隆抗体 | Atg7 polyclonal a

【产品形式】：艾美捷为您提供的Atg7 多克隆抗体经过WB, ELISA等实验验证。推荐使用稀释比率分别为：WB: 1:500-2000。

【背景资料】：Autophagy involves concerted action of more than 20 specific autophagy (ATG) proteins that mediate the formation of a double-membrane vesicle, the autophagosome, which engulfs its substrates and delivers them to the lysosome for degradation. In many cases control of substrate selectivity is mediated by ubiquitin modification. Two ubiquitin-like protein conjugation systems regulate expansion. Atg8 is processed by the Atg4 protease at its C-terminus, activated by the E1-like enzyme Atg7 and conjugated to PE by the E2-like protein Atg3. Atg12–Atg5-Atg16 may act as an E3 ligase for Atg8–PE conjugation, and may dictate the site of conjugation. Atg8 family members in mammals include LC3A, LC3B, LC3C, GABARAP, GABARAPL1 and GABARAPL2 (also known as GATE16). Atg8 (LC3 in mammals) helps determine autophagosome size, and it can be deconjugated from PE by a second Atg4-dependent cleavage. Both Atg5 and Atg7 can be used as markers for autophagy.

英国Viva Bioscience公司是一家研发、生产并销售蛋白降解相关产品的公司。其产品主要用于细胞自噬、泛素化和蛋白酶体研究（也覆盖其他蛋白降解相关的产品），其产品价格合理、质量可靠且具有创新性。目前VIVA Bioscience提供逾460种产品，涉及细胞自噬、蛋白泛素化和讲解相关的所有试剂盒、蛋白、底物以及多种抑制剂、激活剂等全系列产品。作为多家进口品牌的中国区域总代理，艾美捷科技与Viva Bioscience一道为中国科研工作者们提供更好、更新的自噬、泛素化和蛋白酶体等研究工具。

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