20S 蛋白酶体 beta2i亚基 多克隆抗体 | 20S

【产品形式】：艾美捷为您提供的20S 蛋白酶体 beta2i亚基 多克隆抗体经过WB等实验验证。推荐使用稀释比率分别为：WB 1:2000 (human), 1:20000 (mouse)。

【背景资料】：When cells are stimulated with pro-inflammatory cytokines, such as interferon gamma (IFN-ϒ), most of their constitutively expressed proteasomes are replaced with immunoproteasomes, which increase the production of peptides for presentation on MHC class I molecules. During immunoproteasome assembly, the constitutive catalytic亚基s (β1, β2, β5) are replaced by the inducible亚基s beta1i (β1i, LMP2), beta2i (β2i, MECL-1) and beta5i (β5i, LMP7), resulting in changes in proteasome specificity. β1i shows greater chymotrypsin-like substrate specificity when compared to its standard counterpart, β1, whereas the caspase-like activity is reduced and the trypsin-like activity elevated. Pure standard proteasomes are found, for instance, in erythrocytes, whereas spleen tissue contains almost exclusively immunoproteasomes. Most other tissues and cells contain varying mixtures of both standard and immunoproteasomes, and, additionally, intermediate-types of proteasomes; each of which subpopulations can be further separated into two or more subtypes all exhibiting slightly different specific activities.

英国Viva Bioscience公司是一家研发、生产并销售蛋白降解相关产品的公司。其产品主要用于细胞自噬、泛素化和蛋白酶体研究（也覆盖其他蛋白降解相关的产品），其产品价格合理、质量可靠且具有创新性。目前VIVA Bioscience提供逾460种产品，涉及细胞自噬、蛋白泛素化和讲解相关的所有试剂盒、蛋白、底物以及多种抑制剂、激活剂等全系列产品。作为多家进口品牌的中国区域总代理，艾美捷科技与Viva Bioscience一道为中国科研工作者们提供更好、更新的自噬、泛素化和蛋白酶体等研究工具。

点击20S 蛋白酶体 beta2i亚基 多克隆抗体查看更详细产品说明，更多应用、储存、价格、货期等信息请致电400-6800-868垂询Viva Bioscience中国区域授权总代理艾美捷科技有限公司。