DKK1是一种分泌蛋白,也是Wnt信号途径的一个抑制蛋白,在多种恶性肿瘤细胞系中高度表达,在肿瘤的发生、发展中有重要作用.
DKK1 is an inhibitor of the Wnt signaling pathway. Elevated levels of DKK1 in bone marrow plasma and peripheral blood is associated with the presence of osteolytic bone lesions in patients with multiple myeloma.
mol wt:29kDa
Other Aliases: Dickkopf 1; Dickkopf 1 like; Dickkopf homolog 1; Dickkopf related protein 1; DKK 1; hDkk 1; hDkk1; SK