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Purified anti-Microtubule Associated Protein 2ab (MAP2ab)参数介绍>>>>
Clone
MT-08
Isotype
Mouse IgG1, κ
Reactivity
Human, Porcine, Mouse
Immunogen
Microtubule protein enriched for kinesin
Formulation
This antibody is provided in phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide. Final antibody concentration is 0.5 mg/ml.
Preparation
The antibody was purified by affinity chromatography.
Concentration
0.5mg/ml
Recommended Usage
Each lot of this antibody is quality control tested by Western blotting. Western blotting, suggested working dilution(s): Use 5 µg antibody per 5 ml antibody dilution buffer for each mini-gel. It is recommended that the reagent be titrated for optimal performance for each application.
Applications
WB - Quality tested IP, IHC, ICC, ELISA - Reported in the literature
Description
Microtubule associated protein 2 also know as MAP2, has three isoforms that include two high molecular weight forms MAP2A and MAP2B (~280KD), and a low molecular weight form MAB2C (~70KD). MAP2 belongs to the microtubule-associated protein family and expressed in the nervous system. The exact function of MAP2 is unknown but MAPs may stabilize the microtubules against depolymerization. They also seem to have a stiffening effect on microtubules. MAP2 has been shown to interact with Fyn, Grb2, PRKACA, and CPEB1. The MT-08 antibody has been shown to be useful for Western blotting, Immunoprecipitation, Immunohistochemistry (frozen sections), Immunocytochemistry, and ELISA of the human, mouse and porcine MAP2A and MAP2B isoforms.