Fe65 蛋白抗体

Fe65 蛋白抗体产品类别

兔抗人、大、小鼠Fe65蛋白抗体。

产品价格

0.1ml/480元 0.2ml/860元

产品标准

浓缩液(1mg/1ml) 亲和纯化抗体

产品应用

WB=1:100-500 Elisa =1:200-1000 IP=1:20-100 IHC=1:100-500 （石蜡切片需做抗原修复）

Fe65 蛋白抗体产品介绍

Fe65 蛋白(又称作Amyloid beta A4 precursor protein-binding family B member 1)可能与细胞内的APP结构域结合调节内源性的APP。分子量为90kDa。
Amyloid precursor protein (APP), which plays a central role in the pathogenesis of Alzheimer's disease (AD), is a cell-surface protein that is cleaved by gamma-secretase at the transmembrane region into an extracellular amyloid-beta peptide (Ab) and an intracellular tail fragment. This cytoplasmic tail of APP forms a multimeric complex with the nuclear adaptor protein FE65 and the histone acetyltransferase Tip60.1 FE65 is an adaptor protein that bridges APP to certain molecular pathways. FE65 is also highly expressed in neurons and possesses the characteristics of a transcription factor. The interaction between APP and FE65 increases the translocation of APP to the cell surface and the subsequent secretion of Ab. FE65 is thus important in the regulation and trafficking of APPxy-2452R CCL3巨噬细胞炎性蛋白1α抗体
xy-2454R CCL19巨噬细胞炎性蛋白19抗体
xy-1742R CYP3A4细胞色素P450 3A4抗体
xy-1661R CK6细胞角蛋白6抗体
xy-1744R CK7细胞角蛋白7抗体
xy-3239R Phospho-CK17 (Ser44)磷酸化细胞角蛋白17抗体
xy-9405R CC85C卷曲螺旋域蛋白质85C抗体
xy-0049R Caspase-9白介素1-β转化酶样凋亡蛋白酶6抗体
xy-0050R Caspase-9白介素1-β转化酶样凋亡蛋白酶6抗体
xy-1011R CXCR4细胞表面趋化因子受体4抗体
xy-0079R CD19CD19抗体
xy-0732R Cyclooxygenase 2环氧合酶2/前列腺素内过氧化物合成酶2抗体
xy-0512R CD2AP白细胞分化抗原CD2AP抗体
xy-0765R CD3ECD3/CD3-ε 抗体
xy-1093R CHI3L1软骨糖蛋白39抗体
xy-0060R CEA癌胚抗原抗体
xy-0744R CEAcam8癌胚抗原相关细胞粘附分子8抗体
xy-1000R CNPaseC型钠尿肽抗体
xy-1611R Cathepsin K组织蛋白酶K抗体
xy-1615R Cathepsin D组织蛋白酶D抗体
xy-1670R Cathepsin H组织蛋白酶H抗体
xy-3081R phospho-CaMK2 alpha (Tyr231)磷酸化钙/钙调素依赖蛋白激酶2α抗体
xy-3082R Phospho-Caspase-9 (Thr125)磷酸化半胱氨酸蛋白酶9抗体
xy-3083R Phospho-Caspase-9 (Tyr153)磷酸化半胱氨酸蛋白酶9抗体
Fe65 蛋白抗体