The antibody was purified by affinity chromatography.
Concentration
0.5mg/ml
Recommended Usage
Each lot of this antibody is quality control tested by Western blotting. Western blotting, suggested working dilution(s): Use 0.5-1 µg per ml antibody dilution buffer. It is recommended that the reagent be titrated for optimal performance for each application.
Applications
WB-Quality tested ICFC - Reported in the literature
Application References
1.Zhang Z, et al. 2007. Blood 109:4328. (Block) 2.Gorman CL, et al. 2008. J. Immunol. 180:1060. 3.Jenson WA, et al. 1997. Eur J. Immunol. 27:707. 4. Mao H, et al. 2010. J. Virol. 84:4148. PubMed
This product is for in vitro research use only. It is not to be used for commercial purposes. Use of this product to produce products for sale or for diagnostic therapeutic or drug discovery purposes is prohibited. In order to obtain a license to use this product for commercial purposes contact The Regents of the University of California.
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Description
The invariant TCR zeta chain is a member of the CD3 complex associated with the clonotypic alpha/beta TCR hetrodimer. The disulfide-linked TCRzeta homodimers transmit signals following TCR ligation. Loss of TCR zeta expression has been reported in a diverse range of disease states, including autoimmune diseases, many neoplastic conditions and chronic infections, such as tuberculosis and leprosy.
Storage
The antibody solution should be stored undiluted at 4°C.