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Anti-Rat CD8b FITC

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  • ¥1068
  • ebioscience
  • 11-0080-81
  • 2025年07月12日
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    • 文献和实验
    • 技术资料
    • 抗体英文名

      Anti-Rat CD8b FITC

    • 规格

      50ug

    The eBio341 monoclonal antibody reacts with rat CD8β. CD8β is a member of the
    immunoglobulin superfamily which heterodimerizes with CD8α to form the CD8
    antigen expressed on CD4+CD8+, double-positive thymocytes, the majority of MHC class
    I-restricted peripheral T cells, and on some macrophages. CD8β expression is
    absent in athymic mice, which are populated by T-cells expressing CD8α homodimers.
    This has led to the idea that CD8β expression is dependent on the development of T
    cells in the thymus. CD8 binds to MHC class I expressed on the surface of antigen-presenting
    cells during antigen presentation, and participates in T-cell receptor signal transduction
    through association with the kinase Lck.

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