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- 详细信息
- 技术资料
- 抗体英文名：
Anti-Rat CD8b FITC
- 规格：
50ug
The eBio341 monoclonal antibody reacts with rat CD8β. CD8β is a member of the
immunoglobulin superfamily which heterodimerizes with CD8α to form the CD8
antigen expressed on CD4+CD8+, double-positive thymocytes, the majority of MHC class
I-restricted peripheral T cells, and on some macrophages. CD8β expression is
absent in athymic mice, which are populated by T-cells expressing CD8α homodimers.
This has led to the idea that CD8β expression is dependent on the development of T
cells in the thymus. CD8 binds to MHC class I expressed on the surface of antigen-presenting
cells during antigen presentation, and participates in T-cell receptor signal transduction
through association with the kinase Lck.
immunoglobulin superfamily which heterodimerizes with CD8α to form the CD8
antigen expressed on CD4+CD8+, double-positive thymocytes, the majority of MHC class
I-restricted peripheral T cells, and on some macrophages. CD8β expression is
absent in athymic mice, which are populated by T-cells expressing CD8α homodimers.
This has led to the idea that CD8β expression is dependent on the development of T
cells in the thymus. CD8 binds to MHC class I expressed on the surface of antigen-presenting
cells during antigen presentation, and participates in T-cell receptor signal transduction
through association with the kinase Lck.
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Anti-Rat CD8b FITC
¥1068
