SOX2 Antibody

SOX2 Antibody - Product infoApplication
IF, WB, IHC, FCPrimary AccessionP48431ReactivityHumanIsotypeIgG1Clone
Names57CT23.3.4Calculated MW34310 DaSOX2 Antibody - Additional infoGene ID6657Other Names
SOX2; Transcription factor SOX-2Target/Specificity
SOX2 recombinant protein is used to produce this monoclonal antibody.Dilution
IF~~1:100
WB~~1:200~2000
IHC~~1:50~100
FC~~1:10~50Format
Purified monoclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody
is purified through a protein G column, eluted with high and low pH buffers and
neutralized immediately, followed by dialysis against PBS.Storage
Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C
in small aliquots to prevent freeze-thaw cycles.Precautions
SOX2 Antibody is for research use only and not for use in diagnostic or therapeutic
procedures.SOX2 Antibody - Protein InformationNameSOX2Function
Transcription factor that forms a trimeric complex with OCT4 on DNA and controls the
expression of a number of genes involved in embryonic development such as YES1, FGF4,
UTF1 and ZFP206 (By similarity). Critical for early embryogenesis and for embryonic stem
cell pluripotency. May function as a switch in neuronal development. Downstream SRRT target
that mediates the promotion of neural stem cell self-renewal (By similarity). Keeps neural
cells undifferentiated by counteracting the activity of proneural proteins and suppresses
neuronal differentiation (By similarity).Cellular Location
Nucleus.