- ¥1100
- ABGENT
- AM2048a
- 2026年01月16日
- WB IHC IF FC
- H
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- 详细信息
- 文献和实验
- 技术资料
- 抗体名：
SOX2 Antibody
- 抗体英文名：
SOX2 Antibody
- 应用范围：
WB IHC IF FC
- 适应物种：
H
- 克隆性：
多克隆
- 规格：
100UL
IF, WB, IHC, FCPrimary AccessionP48431ReactivityHumanIsotypeIgG1Clone
Names57CT23.3.4Calculated MW34310 DaSOX2 Antibody - Additional infoGene ID6657Other Names
SOX2; Transcription factor SOX-2Target/Specificity
SOX2 recombinant protein is used to produce this monoclonal antibody.Dilution
IF~~1:100
WB~~1:200~2000
IHC~~1:50~100
FC~~1:10~50Format
Purified monoclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody
is purified through a protein G column, eluted with high and low pH buffers and
neutralized immediately, followed by dialysis against PBS.Storage
Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C
in small aliquots to prevent freeze-thaw cycles.Precautions
SOX2 Antibody is for research use only and not for use in diagnostic or therapeutic
procedures.SOX2 Antibody - Protein InformationNameSOX2Function
Transcription factor that forms a trimeric complex with OCT4 on DNA and controls the
expression of a number of genes involved in embryonic development such as YES1, FGF4,
UTF1 and ZFP206 (By similarity). Critical for early embryogenesis and for embryonic stem
cell pluripotency. May function as a switch in neuronal development. Downstream SRRT target
that mediates the promotion of neural stem cell self-renewal (By similarity). Keeps neural
cells undifferentiated by counteracting the activity of proneural proteins and suppresses
neuronal differentiation (By similarity).Cellular Location
Nucleus.
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文献和实验Generation of Antibody Molecules Through Antibody Engineering
been overcome to a large extent using genetic-engineering techniques to produce chimeric mouse/human and completely human antibodies. Such an approach is particularly suitable because of the domain structure of the antibody molecule ( 2 ), where functional
Induced Pluripotent Stem Cells (iPSC) from Cord Blood CD133+ Cells Using Oct4 and Sox2
only two transcription factors OCT4 and SOX2. The methods for establishment and maintenance of CB-derived iPS (CB-iPS) cells are similar, with some modifications, to those for human iPSCs derived from fibroblasts. In particular, this protocol includes a detailed
The importance of antibody molecules was first recognized in the 1890s, when it was shown that immunity to tetanus and diphtheria was caused by antibodies against the bacterial exotoxins (1 ). Around the same time, it was shown that antisera
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