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- 抗体名：
Mouse Irgm1 Antibody (C-term)
- 抗体英文名：
Mouse Irgm1 Antibody (C-term)
- 应用范围：
WB
- 适应物种：
H M
- 克隆性：
多克隆
- 规格：
100UL
WBPrimary AccessionQ60766Other AccessionNP_032352.1ReactivityHuman, MouseIsotypeIgMClone Names403CT8.5.5Calculated MW46552 DaMouse Irgm1 Antibody (C-term) - Additional infoGene ID15944Other Names
Irgm1; Ifi1; Iigp3; Irgm; Immunity-related GTPase family M protein 1; Interferon-inducible GTPase 3; Interferon-inducible protein 1; LPS-stimulated RAW 264.7 macrophage protein 47Target/Specificity
Purified His-tagged Mouse Irgm1 protein was used to produced this monoclonal antibody.Dilution
WB~~1:100~500Format
Purified monoclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Euglobin precipitation followed by dialysis against PBS.Storage
Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.Precautions
Mouse Irgm1 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.Mouse Irgm1 Antibody (C-term) - Protein InformationNameIrgm1SynonymsIfi1, Iigp3, IrgmFunction
Putative GTPase which is required for IFNG-mediated clearance of acute protozoan and bacterial infections. Functions in innate immune response probably through regulation of autophagy. May regulate proinflammatory cytokine production and prevent endotoxemia upon infection. Required for macrophage motility and possibly also for adhesion.Cellular Location
Golgi apparatus membrane. Cell membrane. Cytoplasmic vesicle, phagosome membrane. Cytoplasmic vesicle, autophagosome membrane. Lysosome membrane. Late endosome membrane Cell projection, phagocytic cup. Note=Behaves like an integral membrane protein. Recruited to the plasma membrane around forming phagocytic cups, it remains associated with maturing phagosomes Association with phagosomes is dependent on nucleotide-binding but is IFNG-independent. Preferentially associated with cis- and medial-Golgi. Also detected in late endosomes and lysosomesTissue Location
Expressed in lung and primary macrophages.
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