Pefachrome® TG
Pefachrome® TG is a chromogenic peptide substrate that is cleaved by thrombin at a slow rate. Therefore it is especially suitable for determination of thrombin generation.
Chemical formula: H-β-Ala-Gly-Arg-pNA·2AcOH
MW: 542.6
Kcat: 1.91 s-1 Km: 1.95 mM
参考文献:
References
· Prasa D, Svendsen L, Stürzebecher J.
The ability of thrombin inhibitors to reduce the thrombin activity generated in plasma on extrinsic and intrinsic activation.Thromb and Haemost 1997; 77: 498-503.
· Prasa D, Svendsen L, Stürzebecher J.
Inhibition of thrombin generation in plasma by inhibitors of factor Xa. Thromb and Haemost 1997; 78: 1215-1220.