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- 2025年12月05日
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- 详细信息
- 技术资料
- 保存条件：
4°C, sealed storage, away from moisture and light
- 英文名：
BAY 12-8039
- 库存：
货期：1-2天
- 供应商：
MedChemExpress LLC
- CAS号：
186826-86-8
- 规格：
25 mg/50 mg/100 mg/200 mg/500 mg/1 g
| 规格： | 25 mg | 产品价格： | ￥465.0 |
|---|---|---|---|
| 规格： | 50 mg | 产品价格： | ￥650.0 |
| 规格： | 100 mg | 产品价格： | ￥980.0 |
| 规格： | 200 mg | 产品价格： | ￥1363.0 |
| 规格： | 500 mg | 产品价格： | ￥2400.0 |
| 规格： | 1 g | 产品价格： | ￥3840.0 |
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Moxifloxacin Hydrochloride
CAS No. : 186826-86-8
MCE 国际站：Moxifloxacin Hydrochloride
产品活性：Moxifloxacin Hydrochloride (BAY 12-8039) 是一种口服有效的 8-甲氧基喹诺酮类抗菌活性分子，用于急性细菌性鼻窦炎，慢性支气管炎的急性细菌性加重和感染性肺炎的研究。
研究领域：Anti-infection
作用靶点：Bacterial | Antibiotic
In Vitro: The in vitro activities of Moxifloxacin Hydrochloride (BAY 12-8039) and Amoxicillin are compared by time-kill curve and inhibition of intracellular growth experiments by using a model of bone marrow-derived mouse macrophages infected by L. monocytogenes EGDe. Moxifloxacin acts much more rapidly, beginning to exert its effects in the first 3 h and achieving complete broth sterilization within 24 h of incubation. Moxifloxacin appears to have a protective effect against macrophage lysis, as many cells are still viable after 24 h of incubation.
In Vivo: Moxifloxacin (BAY 12-8039; 12 mg/kg; intravenous injection; once-three times per day; for 7 days; white male Wistar rats) treatment every 8 hours is accompanied by longer survival. Tissue cultures 30 hours after bacterial challenge shows considerably less bacterial overgrowth in the spleens and lungs of moxifloxacin-treated than in salinetreated animals and without being toxic.
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