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- 2025年12月05日
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- 详细信息
- 技术资料
- 保存条件：
4°C, sealed storage, away from moisture and light
- 英文名：
CP 88059 hydrochloride monohydrate
- 库存：
货期：1-2天
- 供应商：
MedChemExpress LLC
- CAS号：
138982-67-9
- 规格：
10 mM * 1 mL/5 mg/10 mg/25 mg/50 mg/100 mg
| 规格： | 10 mM * 1 mL | 产品价格： | ￥675.0 |
|---|---|---|---|
| 规格： | 5 mg | 产品价格： | ￥383.0 |
| 规格： | 10 mg | 产品价格： | ￥614.0 |
| 规格： | 25 mg | 产品价格： | ￥1030.0 |
| 规格： | 50 mg | 产品价格： | ￥1534.0 |
| 规格： | 100 mg | 产品价格： | ￥2388.0 |
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Ziprasidone hydrochloride monohydrate
CAS No. : 138982-67-9
MCE 国际站：Ziprasidone hydrochloride monohydrate
产品活性：Ziprasidone (CP-88059) hydrochloride monohydrate 是一种具有口服活性的 5-HT 和多巴胺 (dopamine) 受体拮抗剂。Ziprasidone hydrochloride monohydrate 对大鼠 D2 (Ki=4.8 nM)、5-HT2A (Ki=0.42 nM) 和 5-HT1A (Ki=3.4 nM) 有亲和作用。
研究领域：GPCR/G Protein | Neuronal Signaling
作用靶点：5-HT Receptor | Dopamine Receptor
In Vitro: Ziprasidone hydrochloride monohydrate (0-500 nM, 150 seconds) blocks wild-type hERG current.
In Vivo: Ziprasidone hydrochloride monohydrate (oral gavage; 20 mg/kg; once daily; 7 weeks) results in weight loss, low level physical activity, high resting energy expenditure and greater capacity for thermogenesis when subjected to cold.
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