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- 2025年12月05日
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- 详细信息
- 技术资料
- 保存条件：
Powder: -20°C, 3 years; 4°C, 2 years.In solvent: -80°C, 6 months; -20°C, 1 month.
- 库存：
货期：1-2天
- 供应商：
MedChemExpress LLC
- CAS号：
82034-46-6
- 规格：
10 mM * 1 mL/5 mg/10 mg/50 mg/100 mg
| 规格： | 10 mM * 1 mL | 产品价格： | ￥314.0 |
|---|---|---|---|
| 规格： | 5 mg | 产品价格： | ￥306.0 |
| 规格： | 10 mg | 产品价格： | ￥490.0 |
| 规格： | 50 mg | 产品价格： | ￥1400.0 |
| 规格： | 100 mg | 产品价格： | ￥2100.0 |
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Loteprednol Etabonate
CAS No. : 82034-46-6
MCE 国际站：Loteprednol Etabonate
产品活性：Loteprednol etabonate (LE) 是口服有效的“软”类固醇，是一种糖皮质激素。Loteprednol etabonate (LE) 具有抗炎活性，可用于验光等眼科研究。
研究领域：Immunology/Inflammation | Vitamin D Related/Nuclear Receptor | Anti-infection
作用靶点：Glucocorticoid Receptor | Bacterial | Antibiotic
In Vivo: Intravenous administration of Loteprednol etabonate (5 mg/kg) to dogs reveals a terminal half-life of 2.8 h, a volume of distribution of 3.7 L/kg, and a total body clearance of 0.9 L/h/kg. Intact loteprednol etabonate was not detectable in the urine. After oral administration of the drug (5 mg/kg) to dogs, only metabolites, but no intact drug, were found in the plasma, an indication for a high first-pass effect.
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