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- 详细信息
- 技术资料
- 保存条件:
-20°C, protect from light, stored under nitrogen
- 英文名:
m-THPC; KW2345
- 库存:
货期:1-2天
- 供应商:
MedChemExpress LLC
- CAS号:
122341-38-2
- 规格:
10 mM * 1 mL/2 mg/5 mg/10 mg
| 规格: | 10 mM * 1 mL | 产品价格: | ¥3295.0 |
|---|---|---|---|
| 规格: | 2 mg | 产品价格: | ¥1450.0 |
| 规格: | 5 mg | 产品价格: | ¥2200.0 |
| 规格: | 10 mg | 产品价格: | ¥3800.0 |
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Temoporfin
CAS No. : 122341-38-2
MCE 国际站:Temoporfin
产品活性:Temoporfin (m-THPC),一种还原卟啉,是有效的第二代光敏剂。Temoporfin 可用于头颈部癌症的光动力疗法研究。
研究领域:Immunology/Inflammation | NF-κB | Metabolic Enzyme/Protease
In Vitro: A detailed confocal fluorescence microscopy study of a human adenocarcinoma shows weak localization of Temoporfin in lysosomes and mitochondria. Instead, it is found to be localized in the endoplasmic reticulum (ER) and the Golgi apparatus.
In Vivo: Temoporfin in liver tissue decreases rapidly in time after initial high levels at 4 h after administration (0.1-0.3 mg/kg). In tumour tissue no decrease in photosensitizer levels occurred, with Temoporfin remaining high up to 48 h after administration.
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