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- 详细信息
- 文献和实验
- 技术资料
- 抗体名：
α2C-AR肾上腺素能受体抗体
- 抗体英文名：
ADRA2C
- 浓度：
1mg/ml
- 应用范围：
科研使用
- 适应物种：
人，大鼠，小鼠，兔
- 克隆性：
单克隆
- 保存条件：
-20℃
- 形态：
液态/粉状
| 英文名称 | ADRA2C |
| 中文名称 | α2C-AR肾上腺素能受体抗体 |
| 别 名 | alpha 2C Adrenergic Receptor; Adra 2c; Adra 2c; ADRA2C; ADRA2L2; ADRA2L2; ADRA2RL2; ADRA2RL2; ADRARL2; ADRARL2; Adrenergic alpha 2C receptor; Adrenoceptor alpha 2C; Alpha 2C adrenergic receptor; Alpha 2C adrenergic receptor subtype C4; Alpha 2C adrenoceptor; Alpha 2C adrenoreceptor; Alpha 2CAR; alpha2 AR C4; alpha2 AR C4; alpha2 C4; alpha2 C4; alpha2C; alpha2C; ALPHA2CAR; alpha2cii-adrenergic receptor; Subtype alpha2 C4; Subtype alpha2 C4; ADA2C_HUMAN. |
| 说 明 书 | 0.2ml |
| 研究领域 | 神经生物学 信号转导 生长因子和激素 细胞膜受体 G蛋白偶联受体 G蛋白信号 |
| 抗体来源 | Rabbit |
| 克隆类型 | Polyclonal |
| 交叉反应 | Human, Mouse, Rat, Dog, Pig, |
| 产品应用 | WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 Flow-Cyt=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 49kDaα2C-AR肾上腺素能受体抗体 |
| 细胞定位 | 细胞膜 |
| 性 状 | Lyophilized or Liquid |
| 浓 度 | 1mg/1ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human ADRA2C/alpha 2C Adrenergic Receptor |
| 亚 型 | IgGα2C-AR肾上腺素能受体抗体 |
| 纯化方法 | affinity purified by Protein A |
| 储 存 液 | Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4 |
| 保存条件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
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文献和实验Distribution of 2A- and 2C-Adrenergic Receptor Immunoreactivity in the Central Nervous System
and no apparent differences in their intracellular effectors. However, clues to the discrete functions of the subtypes have been provided by recent transgenic studies in which targeted mutation of the α2A -AR or overexpression of the α2C -AR in mice reveal
Use of Electron Microscopy in the Detection of Adrenergic Receptors
two second messengers, diacylglycerol and inositol-1,4,5-trisphosphate. The three subtypes of α2 -ARs are designated α2A -, α2B -, and α2C -AR. On binding with agonists, α2 -AR inhibit adenylyl cyclase and calcium channels, but activate potassium channels
and sub-subtypes, and to date, nine distinct AR genes have been identified by molecular cloning, including three α1 -AR subtypes (α1A/D , α1B , and α1C ), three α2 -AR (α2A , α2B , and α2C ) and three β-AR (β1 , β2 , and β3 ) (1 ,2 ). The expression
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