GASKET, GORE-TEX, 3/16OD

SDS-PAGE Western Blotting Protocols

glass plate can be treated with Rain-X to facilitate later removal of the gel. 2. Slide into holder without tightening the screws. 3. Place on pouring stand, making sure that the glass plates are pushed all the way to the bottom before tightening

【第95期】前沿靶点速递：每周医学研究精选

-5[6] 近期在《Nature Cell Biology》发表了一篇研究，揭示了基于PARP1捕获的抗肿瘤耐药新靶标TEX264及其精准药物开发方向。该研究由牛津大学团队完成，发现PARP抑制剂处理后，自噬系统被显著激活以保护肿瘤细胞，其中选择性自噬受体TEX264作为p97共因子，通过其C末端LIR基序识别并结合染色质上捕获的PARP1，介导其从细胞核输出至溶酶体降解。TEX264缺失导致PARP1聚集体累积、DNA损伤加剧和细胞死亡，并可逆转PARPi获得性耐药。临床数据分析显示，HRD

ChIP-Chip E. coli

150 mM NaCl 15ml 5M 1 mM EDTA 1ml 0.5M 1% Triton X 100 5ml 0.1 % Sodium deoxycholate 0.5g 0.1 % SDS 5ml 10%