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文献和实验Generation and Hepatic Differentiation of Human iPS Cells
carrying the four transcription factors POU5F1 (OCT3/4), KLF4, SOX2, and MYC (c-Myc) (Masaki H & Ishikawa T Stem Cell Res 1:105–15, 2007). The differentiation of human iPS cells into hepatic cells was performed by a stepwise protocol (Song Z et al. Cell Res
Hepatic Differentiation of Mesenchymal Stem Cells: In Vitro Strategies
(hepatocytes) and ectodermal (neural cells) cell types in vitro. Whereas unidirectional differentiation into other mesenchymal cell types, including adipocytes, chondrocytes, and osteoblasts, readily occurs in the presence of a simple cocktail of growth factors
Multistage Hepatic Differentiation from Human Induced Pluripotent Stem Cells
Efficient hepatic differentiation technologies designed for patient specific induced pluripotent stem (iPS) cells may provide an unlimited hepatocyte source which can be utilized in drug screening, disease modeling, and cell therapy
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