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- 详细信息
- 询价记录
- 文献和实验
- 技术资料
- 保质期:
1年
- 英文名:
Antithrombin III, Human
- 库存:
大量
- 供应商:
Boatman Biotech
- CAS号:
90170-80-2
- 保存条件:
2-8 ℃
- 规格:
10 IU
抗凝血酶III是一种依赖于肝素的丝氨酸蛋白酶抑制剂,是ー种重要的抗凝血因子,在血浆中承担着70%的抗凝血酶活性,在維持血液生理性凝血与抗凝血平衡中起着重要的作用。在正常人类血浆中浓度约为0.15mg/ml,即约2.3μM。抗凝血酶III是正常人血浆中最重要的丝氨酸蛋白酶抑制剂,在血栓形成过程中,在肝素的催化下,通过与凝血酶(FIIa)或凝血因子IXa、Xa、XIa、XIIa、纤溶酶等丝氨酸蛋白酶以1:1的比例形成复合物,从而使这些酶失去活性,发挥抗凝作用。
来源:
抗凝血酶III(Antithrombin III,AT-III)来源于人血浆,通过离子交换和亲和层析高度纯化;经冷冻干燥制成无菌冻干品,每瓶含10 IU。
| 底 物 | 产 品 应 用 | 规 格 | 货 号 |
| S-2238 | Chromogenic substrate for thrombin | 25 mg | B2238 |
| S-2765 | Chromogenic substrate for factor Xa | 25 mg | B2765 |
| S-2222 | Chromogenic substrate for factor Xa | 25 mg | B2222 |
| S-2732 | Chromogenic substrate for factor Xa | 25 mg | B2732 |
| S-2251 | Chromogenic substrate for plasmin and streptokinase-activated plasminogen | 25 mg | B2251 |
| S-2266 | Chromogenic substrate for Glandular Kallikrein | 25 mg | B2266 |
| S-2288 | Chromogenic substrate for t-PA and a broad spectrum of other serine proteases | 25 mg | B2288 |
| S-2302 | Chromogenic substrate for plasma kallikrein and factor XIIa | 25 mg | B2302 |
| S-2366 | Chromogenic substrate for activated protein C and factor XIa | 25 mg | B2366 |
| S-2403 | Chromogenic substrate for plasmin and streptokinase-activated plasminogen. | 25 mg | B2403 |
| S-2444 | Chromogenic substrate for Urokinase | 25 mg | B2444 |
| S-2586 | Chromogenic substrate for Chymotrypsin | 25 mg | B2586 |
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文献和实验in plasma were reported, leading to the classification of antithrombin in a range from I to IV. It was subsequently shown that these various antithrombin activities were the function of one molecule, antithrombin III, whose name was reduced to antithrombin
Antithrombotic Effects of Naturally Derived Products on Coagulation and Platelet Function
properties); fucus (heparin-like activity); danshen (antithrombin III-like activity and anticoagulant bioavailability); and St. John’s Wort and American Ginseng (interference with drug metabolism). Other supplements, such as high doses of vitamin E (vitamin K
;2、用于扩容;3、治疗低蛋白血症;4、与红细胞搭配输注;5、用于补充营养;6、用于提高免疫力;7、促进伤口愈合;8、FFP量不足(�10-15ml/kg) 各种原因引起的多种凝血因子或抗凝血酶III缺乏并伴有出血表现 1、无合理输血理由;2、用于扩容;3、治疗低蛋白血症;4、与红细胞搭配输注;5、用于补充营养;6、用于提高免疫力;7、FFP量不足(�10-15ml/kg) 血小板 1、血小板�50×109
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