CD161 Antibody (FITC) 抗体，orb15

类别: Antibodies

产品子类型: Primary Antibody

描述: Mouse monoclonal antibody conjugated to FITC which recognizes CD161 that is expressed in a subset of NK cells predominantly in intestinal epithelium and liver that participates in inhibitory role on natural killer (NK) cells cytotoxicity and also plays role as a lectin that binds to the terminal carbohydrate Gal-alpha(1,3)Gal epitope as well as to the N-acetyllactosamine epitope.

克隆号: 10/78

别名: NKRP1A, Klrb

应用说明: Flow cytometry: Recommended dilution: 2-5 μg/ml.

免疫原: Splenic cells purified from the LEW rat

防腐剂: Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide

纯化方法: Purified antibody is conjugated with fluorescein isothiocyanate (FITC) under optimum conditions and unconjugated antibody and free fluorochrome are removed by size-exclusion chromatography.

特异性: The mouse monoclonal antibody 10/78 recognizes CD161, an approximately 30 kDa type II transmembrane C-type lectin receptor, expressed on the plasma membrane of NK cells, dendritic cells, activated monocytes and a subset of T cells as a disulphide-linked homodimer. A common extracellular epitope on rat CD161a and b isoforms is detected.

研究领域: Immunology & Inflammation

UniProt ID: Q0ZUP0

Entrez 基因 ID: 689817

保存条件: Store at 2-8°C. Protect from prolonged exposure to light. Do not freeze.

备注: For research use only.