Full length human FIH expressed in E.coli BL21 (DE3) cells
规格:
100 ug
Mouse monoclonal to FIH (FITC). FIH, Factor inhibiting HIF1 (hypoxia-inducible factor), is an asparaginyl hydroxylase. FIH in conjunction with VHL represses HIF-1 transcriptional activity by disrupting the interaction of HIF-1 with the transcriptional co-activators CBP/p300, and by recruiting histone deacetylases. FIH activity is inhibited during hypoxia (1-3). Recent studies show that low nuclear expression of FIH is a strong independent prognostic factor for a poor overall survival in clear cell renal cell carcinoma..
产品名:FIH antibody (FITC)
货号:orb147841
产品中文名:FIH 抗体 (FITC)
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