A synthetic peptide corresponding to a sequence in the middle region of human SOCS3(71-85aa RDSSDQRHFFTLSVK), identical to the related mouse sequence, different from the related rat sequence by one amino acid.
规格:
100 ug
Rabbit Polyclonal to SOCS3. SOCS3(Suppressor of cytokine signaling 3) is a protein that in humans is encoded by the SOCS3 gene. SOCS3 is transiently expressed by multiple cell lineages within the immune system and functions predominantly as a negative regulator of cytokines that activate the JAK-STAT3 pathway. This gene encodes a member of the STAT-induced STAT inhibitor (SSI), also known as suppressor of cytokine signaling (SOCS), family. SSI family members are cytokine-inducible negative regulators of cytokine signaling. The expression of this gene is induced by various cytokines, including IL6, IL10, and interferon (IFN)-gamma. The protein encoded by this gene can bind to JAK2 kinase, and inhibit the activity of JAK2 kinase. For signaling of IL-6, Epo, GCSF and Leptin, binding of SOCS3 to the respective cytokine receptor has been found to be crucial for the inhibitory function of SOCS3. Studies of the mouse counterpart of this gene suggested the roles of this gene in the negative regulation of fetal liver hematopoiesis, and placental development.
产品名:SOCS3 antibody
货号:orb76221
产品中文名:SOCS3 抗体
产品详情链接:https://www.biorbyt.com.cn/socs3-antibody-orb76221.html 武汉博欧特生物科技有限公司(www.wuhanbio.com )为英国品牌Biorbyt(www.biorbyt.com )中国办事处,即biorbyt中国总代理,即biorbyt总代。负责biorbyt品牌产品在中国市场的推广、销售及售后服务。为您提供各种biorbyt原装进口产品,主推四大类: