- ￥5148
- Biorbyt
- orb67250
- 英国
- 2026年08月06日
- WB
- Rabbit
- Human
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- 文献和实验
- 技术资料
- 抗体名：
SYVN1 (M) Antibody, Rabbit Polyclonal 抗体
- 抗体英文名：
SYVN1 (M) Antibody, Rabbit Polyclonal
- 应用范围：
WB
- 宿主：
Rabbit
- 适应物种：
Human
- 保质期：
12 months from date of receipt.
- 抗原来源：
详询
- 目录编号：
orb67250
- 级别：
科研
- 库存：
99
- 供应商：
Biorbyt
- 标记物：
Unconjugated
- 克隆性：
Polyclonal
- 保存条件：
详询
- 免疫原：
详询
- 规格：
100 ul
描述: Rabbit polyclonal to SYVN1.E3 ubiquitin-protein ligase synoviolin (SYVN1) is a multi-pass membrane protein that belongs to theHRD1 family. It acts as an E3 ubiquitin-protein ligase which accepts ubiquitin specifically fromendoplasmic reticulum-associated UBC7 E2 ligase and transfers it to substrates, promoting theirdegradation. SYVN1 protects cells from ER stress-induced apoptosis and protects neurons fromapoptosis induced by polyglutamine-expanded huntingtin (HTT) or unfolded GPR37 by promotingtheir degradation. It sequesters p53/TP53 in the cytoplasm and promotes its degradation, therebynegatively regulating its biological function in transcription, cell cycle regulation and apoptosis.
别名: anti-SYVN1 antibody,anti-E3 ubiquitinprotein ligase synoviolin antibody,anti-Synovial apoptosis inhibitor 1 antibody,anti-HRD1 antibody,anti-KIAA1810 antibody
应用稀释比例: WB:1:500-1:2000
免疫原: middle region of human SYVN1
分子量: 68
防腐剂: 0.01% NaN3
纯度: Affinity purification
研究领域: Cell Biology
UniProt ID: Q86TM6
保存条件: Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
备注: For research use only.
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文献和实验Polyclonal Antibody Production
Zealand White Rabbits and have them delivered to the ARC. Don’t put all your eggs in one basket only using one rabbit. Let them get accustomed to there home there for two weeks before the first pre-bleed. Pre-bleed
Polyclonal Antibody Production
Polyclonal Antibody Production Very useful for rapid and simple generation of antibodies for western blots, ELISA assays, and immunoprecipitation. Rabbit Immunization Initial Preparation Your antigen
Generation and Selection of Rabbit Antibody Libraries by Phage Display
The rabbit antibody repertoire is an exceptional source for both polyclonal antibodies (pAbs) and monoclonal antibodies (mAbs) that combine high specificity with high avidity and affinity, respectively. In contrast to rabbit pAbs
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