Beta Defensin-4 Rat Recombinant protein. Defensins are cationic peptides with a large spectrum of antimicrobial activity that comprise an important arm of the innate immune system. The Alpha defensins are differentiated from the Beta-defensins by the pairing of their 3 disulfide bonds. 4 human Beta-defensins have been identified to date; BD-1, BD-2, BD-3 and BD-4. Beta-defensins are expressed on some leukocytes and at epithelial surfaces. In addition to their direct antimicrobial activities, they are chemoattractant towards immature dendritic cells and memory T cells. The beta-defensin proteins are expressed as the C-terminal portion of precursors and are released by proteolytic cleavage of a signal sequence and, in the case of BD-1 (36 a.a.), a propeptide region. Beta-defensins contain a six-cysteine motif that forms three intra-molecular disulfide bonds. Beta-Defensins are 3-5 kDa peptides ranging in size from 33-47 amino acid residues.
产品名:Rat BD 4 protein
货号:orb167974
产品中文名:Rat BD 4 protein
产品别称:Beta-defensin 4 protein, BD-4 protein, BD-2 protein, Defensin protein, beta 4 protein, RBD-2 protein, RBD-4 protein, Defb4 protein, Defb2 protein, Defb3.
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