重组狗 IL17 / IL17A 蛋白(产品说明)
蛋白名称:Canine IL17 / IL17A Protein
蛋白构建:A DNA sequence encoding the canine IL17A (NP_001159350.1)(Gly26-Ala155) was expressed with a N-terminal Met.
表达宿主:E. coli
蛋白纯度:> 90 % as determined by SDS-PAGE
蛋白活性:1. Measured by its binding ability in a functional ELISA. Immobilized Canine IL17A (cat: 70102-DNAE) at 10 μg/ml (100 μl/well) can bind human IL17Ra (Cat:10895-H03H), The EC50 of human IL17Ra (Cat:10895-H03H) is 6.0-15.0 ng/ml.2. Measured by its ability to induce IL-6 secretion by HFF human foreskin fibroblast cells. The ED50 for this effect is typically 1-5 ng/mL.
蛋白内毒素:Please contact us for more information.
预测N端:Met
蛋白分子量:The recombinant canine IL17A comprises 131 amino acids and has a predicted molecular mass of 15.2 kDa. The apparent molecular mass of the protein is approximately 15 kDa in SDS-PAGE under reducing conditions due to glycosylation.
蛋白NP号:NP_001159350.1
蛋白氨基酸序列:Gly26-Ala155
蛋白标签:Native
蛋白保存条件:Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
1, Deng, J; et al. The effects of interleukin 17A on left stellate ganglion remodeling are mediated by neuroimmune communication in normal structural hearts. Int. J. Cardiol., Pubmed: 30642646