- ￥780 - 39880
- Sino Biological
- 北京
- 51112-MNAH
- 2026年01月26日
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- 详细信息
- 询价记录
- 文献和实验
- 技术资料
- 保存条件：
-20℃ to -80℃
- 保质期：
12个月
- 英文名：
Recombinant Mouse M-CSF / CSF-1 Protein (ECD)
- 库存：
99
- 供应商：
北京义翘神州科技股份有限公司
- 规格：
1.00 mg/5.00 µg/20.00 µg/100.00 µg
| 规格： | 1.00 mg | 产品价格： | ￥39880.0 |
|---|---|---|---|
| 规格： | 5.00 µg | 产品价格： | ￥780.0 |
| 规格： | 20.00 µg | 产品价格： | ￥1780.0 |
| 规格： | 100.00 µg | 产品价格： | ￥4980.0 |
小鼠 M-CSF蛋白|M-CSF protein|M-CSF(Mouse, Native)（产品说明）
蛋白名称：M-CSF蛋白, M-CSF protein
蛋白构建：A DNA sequence encoding the mouse CSF1 (P07141-1) (Met1-Glu262) was expressed.
表达宿主：HEK293 Cells
蛋白纯度：> 95 % as determined by SDS-PAGE
蛋白活性：1. Immobilized mouse CSF1 at 10 μg/ml (100 μl/well) can bind mouse CSF1R-Fch (Cat:50059-M03H), The EC50 of mouse CSF1R-Fch (Cat:50059-M03H) is 0.04-0.1 μg/ml. 2. Measured in a cell proliferation assay using M‑NFS‑60 mouse myelogenous leukemia lymphoblast cells. The ED50 for this effect is typically 3-15 ng/ml.
蛋白内毒素：< 1.0 EU per μg of the protein as determined by the LAL method
预测N端：Lys 33
蛋白分子量：The recombinant mouse CSF1 comprises 230 amino acids and has a predicted molecular mass of 26 kDa. The apparent molecular mass of the protein is approximately 45 kDa in SDS-PAGE under reducing conditions due to glycosylation.
蛋白NP号：P07141-1
蛋白氨基酸序列：Met1-Glu262
蛋白标签：Native
蛋白保存条件：Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
蛋白名称：M-CSF蛋白, M-CSF protein
蛋白构建：A DNA sequence encoding the mouse CSF1 (P07141-1) (Met1-Glu262) was expressed.
表达宿主：HEK293 Cells
蛋白纯度：> 95 % as determined by SDS-PAGE
蛋白活性：1. Immobilized mouse CSF1 at 10 μg/ml (100 μl/well) can bind mouse CSF1R-Fch (Cat:50059-M03H), The EC50 of mouse CSF1R-Fch (Cat:50059-M03H) is 0.04-0.1 μg/ml. 2. Measured in a cell proliferation assay using M‑NFS‑60 mouse myelogenous leukemia lymphoblast cells. The ED50 for this effect is typically 3-15 ng/ml.
蛋白内毒素：< 1.0 EU per μg of the protein as determined by the LAL method
预测N端：Lys 33
蛋白分子量：The recombinant mouse CSF1 comprises 230 amino acids and has a predicted molecular mass of 26 kDa. The apparent molecular mass of the protein is approximately 45 kDa in SDS-PAGE under reducing conditions due to glycosylation.
蛋白NP号：P07141-1
蛋白氨基酸序列：Met1-Glu262
蛋白标签：Native
蛋白保存条件：Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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文献和实验该产品被引用文献
1, Qi, R; et al. Ethanol extract of Elephantopus scaber Linn. Attenuates inflammatory response via the inhibition of NF-κB signaling by dampening p65-DNA binding activity in lipopolysaccharide-activated macrophages. Journal of ethnopharmacology, PMID: 31877363
2, Qiu, J; et al. ZBTB20-mediated titanium particle-induced peri-implant osteolysis by promoting macrophage inflammatory responses. Biomaterials science, PMID: 32363359
3, Hu, H; et al. Correction to: Castor1 overexpression regulates microglia M1/M2 polarization via inhibiting mTOR pathway. Metabolic brain disease, PMID: 36692625
4, Sun, Y; et al. Colorectal cancer-derived extracellular vesicles containing HSP70 enhance macrophage phagocytosis by up-regulating MARCO expression. Experimental cell research, PMID: 36958650
5, You, Y; et al. Fibroblast-derived CXCL14 aggravates crystalline silica-induced pulmonary fibrosis by mediating polarization and recruitment of interstitial macrophages. Journal of hazardous materials, PMID: 37688871
6, Ouyang, Y; et al. FGFR3 alterations in bladder cancer stimulate serine synthesis to induce immune-inert macrophages that suppress T-cell recruitment and activation. Cancer research, PMID: 37768887
7, Dong, Y; et al. A clinical-stage Nrf2 activator suppresses osteoclast differentiation via the iron-ornithine axis. Cell metabolism, PMID: 38569557
8, Ma, Z; et al. Extracellular vesicles containing MFGE8 from colorectal cancer facilitate macrophage efferocytosis. Cell communication and signaling : CCS, PMID: 38802814
9, Luo, S; et al. Cholinergic macrophages promote the resolution of peritoneal inflammation. Proceedings of the National Academy of Sciences of the United States of America, PMID: 38923993
10, Huang, XR; et al. Macrophage autophagy protects against acute kidney injury by inhibiting renal inflammation through the degradation of TARM1. Autophagy, PMID: 39193910
11, Zhang, C; et al. Secreted PTEN binds PLXDC2 on macrophages to drive antitumor immunity and tumor suppression. Developmental cell, PMID: 39197453 1
2, Chen, C; et al. CD5L up-regulates the TGF-β signaling pathway and promotes renal fibrosis. Life sciences, PMID: 39127319 1
3, Liu, W; et al. SGLT2 inhibitor promotes ketogenesis to improve MASH by suppressing CD8+ T cell activation. Cell metabolism, PMID: 39243758 1
4, Yan, H; et al. Hexokinase 2 senses fructose in tumor-associated macrophages to promote colorectal cancer growth. Cell metabolism, PMID: 39471815 1
5, Yu, S; et al. PKM2-mediated STAT3 phosphorylation promotes acute liver failure via regulating NLRP3-dependent pyroptosis. Communications biology, PMID: 39722076 1
6, Yu, Z; et al. Programmed surface platform orchestrates anti-bacterial ability and time-sequential bone healing for implant-associated infection. Biomaterials, PMID: 39190942 1
7, Zhang, F; et al. A novel zinc ferrite nanoparticle protects against MSU-induced gout arthritis via Nrf2/NF-κB/NLRP3 pathway. Life sciences, PMID: 39983819 1
8, Chen, X; et al. Bioactive Decellularized Extracellular Matrix Platform Integrating Multifunctional Nanozymes and Cell-Laden Microgels for Acute Liver Failure Treatment. ACS nano, PMID: 39950852 1
9, Wu, XN; et al. Adenosine A2A Receptor Activation Alleviated Disease of Mice with Systemic Candida albicans Infection by Regulating Macrophage Function. Journal of inflammation research, PMID: 40065909
20, Cheng, S; et al. Shexiang Baoxin Pill alleviates atherosclerosis by inhibiting macrophage-mediated inflammation via suppressing KMT5A mediated Irf7 transcription. Journal of ethnopharmacology, PMID: 40252984
21, Rong, K; et al. Inflammatory macrophage-derived itaconate inhibits DNA demethylase TET2 to prevent excessive osteoclast activation in rheumatoid arthritis. Bone research, PMID: 40500265 2
2, Liu, H; et al. From inflammation to healing: the crucial role of GPR91 activation and SDH inhibition in chronic diabetic wound recovery. Stem cell research & therapy, PMID: 40702577 2
3, Yang, Y; et al. Blockade of TLR2 activation in macrophages by self-assembled hyaluronic acid nanoparticles alleviates psoriasis-like skin dermatitis. International journal of biological macromolecules, PMID: 40885365 2
4, Lao, A; et al. Metabolic and immunomodulatory control of type 2 diabetes via generating cellular itaconate reservoirs by inflammatory-targeting gene-therapy nanovesicles. Trends in biotechnology, PMID: 40925799
2, Qiu, J; et al. ZBTB20-mediated titanium particle-induced peri-implant osteolysis by promoting macrophage inflammatory responses. Biomaterials science, PMID: 32363359
3, Hu, H; et al. Correction to: Castor1 overexpression regulates microglia M1/M2 polarization via inhibiting mTOR pathway. Metabolic brain disease, PMID: 36692625
4, Sun, Y; et al. Colorectal cancer-derived extracellular vesicles containing HSP70 enhance macrophage phagocytosis by up-regulating MARCO expression. Experimental cell research, PMID: 36958650
5, You, Y; et al. Fibroblast-derived CXCL14 aggravates crystalline silica-induced pulmonary fibrosis by mediating polarization and recruitment of interstitial macrophages. Journal of hazardous materials, PMID: 37688871
6, Ouyang, Y; et al. FGFR3 alterations in bladder cancer stimulate serine synthesis to induce immune-inert macrophages that suppress T-cell recruitment and activation. Cancer research, PMID: 37768887
7, Dong, Y; et al. A clinical-stage Nrf2 activator suppresses osteoclast differentiation via the iron-ornithine axis. Cell metabolism, PMID: 38569557
8, Ma, Z; et al. Extracellular vesicles containing MFGE8 from colorectal cancer facilitate macrophage efferocytosis. Cell communication and signaling : CCS, PMID: 38802814
9, Luo, S; et al. Cholinergic macrophages promote the resolution of peritoneal inflammation. Proceedings of the National Academy of Sciences of the United States of America, PMID: 38923993
10, Huang, XR; et al. Macrophage autophagy protects against acute kidney injury by inhibiting renal inflammation through the degradation of TARM1. Autophagy, PMID: 39193910
11, Zhang, C; et al. Secreted PTEN binds PLXDC2 on macrophages to drive antitumor immunity and tumor suppression. Developmental cell, PMID: 39197453 1
2, Chen, C; et al. CD5L up-regulates the TGF-β signaling pathway and promotes renal fibrosis. Life sciences, PMID: 39127319 1
3, Liu, W; et al. SGLT2 inhibitor promotes ketogenesis to improve MASH by suppressing CD8+ T cell activation. Cell metabolism, PMID: 39243758 1
4, Yan, H; et al. Hexokinase 2 senses fructose in tumor-associated macrophages to promote colorectal cancer growth. Cell metabolism, PMID: 39471815 1
5, Yu, S; et al. PKM2-mediated STAT3 phosphorylation promotes acute liver failure via regulating NLRP3-dependent pyroptosis. Communications biology, PMID: 39722076 1
6, Yu, Z; et al. Programmed surface platform orchestrates anti-bacterial ability and time-sequential bone healing for implant-associated infection. Biomaterials, PMID: 39190942 1
7, Zhang, F; et al. A novel zinc ferrite nanoparticle protects against MSU-induced gout arthritis via Nrf2/NF-κB/NLRP3 pathway. Life sciences, PMID: 39983819 1
8, Chen, X; et al. Bioactive Decellularized Extracellular Matrix Platform Integrating Multifunctional Nanozymes and Cell-Laden Microgels for Acute Liver Failure Treatment. ACS nano, PMID: 39950852 1
9, Wu, XN; et al. Adenosine A2A Receptor Activation Alleviated Disease of Mice with Systemic Candida albicans Infection by Regulating Macrophage Function. Journal of inflammation research, PMID: 40065909
20, Cheng, S; et al. Shexiang Baoxin Pill alleviates atherosclerosis by inhibiting macrophage-mediated inflammation via suppressing KMT5A mediated Irf7 transcription. Journal of ethnopharmacology, PMID: 40252984
21, Rong, K; et al. Inflammatory macrophage-derived itaconate inhibits DNA demethylase TET2 to prevent excessive osteoclast activation in rheumatoid arthritis. Bone research, PMID: 40500265 2
2, Liu, H; et al. From inflammation to healing: the crucial role of GPR91 activation and SDH inhibition in chronic diabetic wound recovery. Stem cell research & therapy, PMID: 40702577 2
3, Yang, Y; et al. Blockade of TLR2 activation in macrophages by self-assembled hyaluronic acid nanoparticles alleviates psoriasis-like skin dermatitis. International journal of biological macromolecules, PMID: 40885365 2
4, Lao, A; et al. Metabolic and immunomodulatory control of type 2 diabetes via generating cellular itaconate reservoirs by inflammatory-targeting gene-therapy nanovesicles. Trends in biotechnology, PMID: 40925799
相关实验
网络 二、集落刺激因子（CSF) 骨髓造血干细胞体外半固体培养技术的建立和重组集落刺激因子（colony-stimulating factor,CSF)的问世给集落刺激因子的研究提供了前提。根据细胞因子刺激不同造血细胞系或不同分化阶段的细胞在半固体培养基中形成不同细胞集落，分别命名为粒细胞CSF（G-CSF）、巨噬细胞CSF（M-CSF）、粒细胞和巨噬
小鼠巨噬细胞集落刺激因子(M-CSF)ELISA试剂盒 说明书
3. 根据样品 OD 值在该曲线图上查出相应 M-CSF 含量。 试剂盒性能 1. 灵敏度 ： 最小的M-CSF 检测浓度小于 16.5 pg/ml。 2. 特异性： 可同时检测重组或天然的小鼠 M-CSF 。 不与 小鼠其它细胞因子有交叉反应。 3. 重复性：板内、板见变异系数均小于10.3％。 注意事项 1. 以上标准孔及待 测 样品均建议做复孔，每次测定应同时 做 标准曲线。
人巨噬细胞集落刺激因子(M-CSF)ELISA试剂盒 说明书
3. 根据样品 OD 值在该曲线图上查出相应 M-CSF 含量。 试剂盒性能 1. 灵敏度 ： 最小的M-CSF 检测浓度小于 16.5 pg/ml。 2. 特异性： 可同时检测重组或天然的人 M-CSF 。 不与 人其它细胞因子有交叉反应。 3. 重复性：板内、板见变异系数均小于10.3％。 注意事项 1. 以上标准孔及待 测 样品均建议做复孔，每次测定应同时 做 标准曲线。
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重组小鼠 M-CSF / CSF-1蛋白 (ECD)
￥780 - 39880
