BLT2 Receptor Polyclonal Antib

Antigen: human BLT2 receptor amino acids 325-338 • Host: rabbit • Cross Reactivity: (+) human and mouse BLT2 receptor • Application(s): WB (recommended primarily for transfected cells) • The human BLT2 receptor is a 358 amino acid GPCR with approximately 40% homology to BLT1 at the amino acid level. The BLT2 receptor is more broadly expressed than the BLT1 receptor, with highest levels observed in liver, spleen, ovary, intestine, and peripheral blood leukocytes. Activation of the BLT2 receptor by LTB4 leads to Ca2+ mobilization as well as decreases in cyclic AMP, indicating interaction of the receptor with Gq and Gi classes of G-proteins.