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Neobioscience
- 保存条件：
-20
- 规格：
1 mg
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文献和实验and sensitivity of these ultra-high accuracy mass analysers is such that metabolite signals from molecules containing naturally abundant elemental isotopes (e.g. 13 C, 41 K, 15 N, 17 O, 34 S, and 37 Cl) are visible in the data. Such is the instruments precision
Benzydamine N-Oxygenation as a Measure of Flavin-Containing Monooxygenase Activity
Benzydamine is a nonsteroidal anti-inflammatory drug that undergoes flavin-containing monooxygenase (FMO)-dependent metabolism to a stable N -oxide. This metabolite can be quantified with high specificity and sensitivity by using a simple
High-Performance Liquid Chromatography-Mass Spectrometry (HPLC-MS)-Based Drug Metabolite Profiling
of characteristic isotope patterns from either the incorporation of stable isotopes (e.g. 13 C, 15 N) or naturally occurring isotope patterns from substituents on the molecule (e.g. 35/37 Cl, 79/81 Br) can also provide a useful handle on the drug and its metabolites
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