Features and Benefits
Contents
88% AMP-PNP (from N), 4.5% lithium, 6% water
Other Notes
仅用于生命科学研究。不可用于诊断。
Quality
Contaminants: ≤1.5% Pi , <0.1% ATP (enzymatically)
Application
AMP-PNP is a competitive inhibitor of most ATP-dependent systems. A good substrate for enzymes hydrolyzing between the α- and β-phosphorus atom, yet is resistant to enzymes cleaving between the β- and γ-phosphorus atom. Substrate of snake venom phosphodiesterase and adenylate cyclase.
AMP-PNP has been used for two-motor fluorescence assay.
General description
AMP-PNP (adenylyl-imidodiphosphate) is a non-hydrolysable analogue of ATP. It inhibits fast axonal transport and facilitates the interaction between membranous organelles and microtubules.