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Recombinant Ovine Growth Hormo

ne Binding Protein

价格￥1080 - 96600

品牌PROSPEC
产地以色列
货号cyt-470
更新日期2026年02月07日

上海经科化学科技有限公司

16 年钻石会员

规格：	5ug	产品价格：	￥1080.0
规格：	20ug	产品价格：	￥2415.0
规格：	1mg	产品价格：	￥96600.0

CATALOGUE NUMBER

CYT-470

SYNONYMS

GHR, G/.H-BP, GH receptor, Somatotropin receptor.

INTRODUCTION

G/.H-BP is a transmembrane receptor for growth hormone. Binding of growth hormone to the receptor leads to receptor dimerization and the activation of an intra- and intercellular signal transduction pathway leading to growth. A common alternate allele of this gene, called GHRd3, lacks exon three and has been well-characterized. Mutations in this gene have been associated with Laron syndrome, also known as the growth hormone insensitivity syndrome (GHIS), a disorder characterized by short stature. Other splice variants, including one encoding a soluble form of the protein (GHRtr), have been observed but have not been thoroughly characterized.

DESCRIPTION

Growth Hormone Binding Protein Ovine Recombinant produced in E.Coli is a single, non-glycosylated, polypeptide chain containing 237 amino acids and having a molecular mass of 28 kDa.
G/.H-BP is purified by proprietary chromatographic techniques.

SOURCE

Escherichia Coli.

PHYSICAL APPEARANCE

Sterile Filtered White lyophilized (freeze-dried) powder.

FORMULATION

G/.H-BP was lyophilized from a concentrated (1mg/ml) solution with 0.0045mM NaHCO3.

SOLUBILITY

It is recommended to reconstitute the lyophilized Growth Hormone Binding Protein in sterile 18MΩ-cm H2O not less than 100µg/ml, which can then be further diluted to other aqueous solutions.

STABILITY

Lyophilized Growth Hormone Binding Protein although stable at room temperature for 3 weeks, should be stored desiccated below -18°C. Upon reconstitution G/.H-BP should be stored at 4°C between 2-7 days and for future use below -18°C.
For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).
Please prevent freeze-thaw cycles.

PURITY

Greater than 95.0% as determined by:
(a) Analysis by SEC-HPLC.
(b) Analysis by SDS-PAGE.

AMINO ACID SEQUENCE

The sequence of the first five N-terminal amino acids was determined and was found to be Ala-Phe-Ser-Gly-Ser.

SAFETY DATA SHEET

SDS

USAGE

ProSpec's products are furnished for LABORATORY RESEARCH USE ONLY.They may not be used as drugs,agricultural or pesticidal products, food additives or household chemicals.

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498 人阅读发布时间：2024-08-27 15:52

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Recombinant Ovine Growth Hormone Binding Protein

￥1080 - 96600

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Recombinant Ovine Growth Hormo