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文献和实验Delivery of RNA Interference to Peripheral Neurons In Vivo Using Herpes Simplex Virus
replication-defective vectors based on herpes simplex virus (HSV). This method can be utilised to obtain a better understanding of gene function, validate novel gene targets in drug discovery and potentially develop new RNAi-mediated
Gene Transfer to Glial Tumors Using Herpes Simplex Virus
. The first strategy involves the use of viral vectors that are replication-competent, but depend on attributes unique to the tumor cell to support viral growth. Both replication-competent adenovirus and herpes simplex virus (HSV) vectors have been employed in pre
Generation of Recombinant Herpes Simplex Virus Ampiicons
The herpes simplex virus type 1 (HSV-1) amphcon has been developed as a novel eukaryotic expression vector, which contains an HSV-1 ori for DNA replication and a pac signal for cleaving/packaging genomes into viral
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