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- 详细信息
- 文献和实验
- 技术资料
- 保存条件:
4°C避光
- 英文名:
RHODAMINE 123 70010
- 库存:
99
- 供应商:
Biotium
- CAS号:
62669-70-9
Rhodamine 123 is a popular green fluorescent mitochondrial dye that stains mitochondria in living cells in a membrane potential-dependent fashion. It is widely used in flow cytometry studies involving mitochondrial membrane potential. Please also see Dihydrorhodamine 123 and its HCl salt (10055 and 10056).
- λEx/λEm (MeOH) = 505/534 nm
- ε (505 nm, MeOH) = 97,000
- Orange red solid soluble in DMSO or DMF
- Store at 4°C and protect from light, especially in solution
- C21H17ClN2O3
- MW: 381
- [62669-70-9]
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文献和实验【求助】Rhodamine 123 荧光强度和线粒体膜势能问题,求解!
lanzhou3242 我想问一下,到底是 Rhodamine 123黄绿色荧光强度越强,线粒体膜势能越高,还是相反? 有的说Rhodamine 123进入活细胞的线粒体后显示的荧光是弱的或者是不发光的, 而有的说被活细胞线粒体俘获后显示很强的荧光强度, 我做药物对细胞凋亡的影响,是不是control应该很强,而随着凋亡的增加,其线粒体膜势能降低,所以黄绿色荧光强度更弱? fis1314
, representing a built-in obstacle to therapeutic ratio. Constitutive and induced MDR activity can be detected in cellular subsets of disaggregated tissues, using the fluorescent substrates Rhodamine 123 and Hoechst 33342 for ABCB1 (also known as P-gp and MDR
线粒体在细胞凋亡的过程中起着枢纽作用,多种细胞凋亡刺激因子均可诱导不同的细胞发生凋亡,而线粒体跨膜电位DYmt的下降,被认为是细胞凋亡级联反应过程中最早发生的事件,它发生在细胞核凋亡特征(染色质浓缩、DNA断裂)出现之前,一旦线粒体DYmt崩溃,则细胞凋亡不可逆转。线粒体跨膜电位的存在,使一些亲脂性阳离子荧光染料如Rhodamine 123、3,3-Dihexyloxacarbocyanine iodide[DiOC6(3)]、Tetrechloro












