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- 详细信息
- 文献和实验
- 技术资料
- 服务名称：
PCR芯片
- 提供商：
SABio
| Product | Species | Technology | Cat. No. |
| PI3K-AKT Signaling Pathway PCR Array | Human | Gene Expression | PAHS-058Z |
| PI3K-AKT Signaling Pathway PCR Array | Mouse | Gene Expression | PAMM-058Z |
| PI3K-AKT Signaling Pathway PCR Array | Rat | Gene Expression | PARN-058Z |
| PI3K-AKT Signaling Pathway PCR Array | Zebrafish | Gene Expression | PAZF-058Z |
AKT and PI3K Family Members and Their Regulators: AKT1, AKT2, AKT3, BTK, GRB10, GRB2, HSPB1, ILK, MTCP1, PDK2, PDPK1, PIK3CA (p110a), PIK3CG, PIK3R1 (p85a), PIK3R2 (p85b), PAK1, PRKCA, PRKCB, PRKCZ, PTEN, TCL1A. IGF-1 Signaling Pathway: CSNK2A1, ELK1, FOS, GRB2, HRAS, IGF1, IGF1R, IRS1, JUN, MAP2K1, MAPK3, MAPK8, PTPN11, RAF1, RASA1, SHC1, SOS1, SRF. Inactivation of Gsk3 and the Accumulation of β-Catenin: ADAR, AKT1, APC, CCND1, CD14, CTNNB1, EIF2AK2, GJA1, GSK3B, IRAK1, MYD88, NFKB1, PDK1, TIRAP, TLR4, TOLLIP. PI3K Subunit p85 Genes and Regulation of Actin Organization and Cell Migration:CDC42, PDGFRA, RAC1, RHOA, WASL. PTEN Dependent Cell Cycle Arrest and Apoptosis: AKT1, CDKN1B (p27), FASLG, FOXO3, GRB2, ILK, ITGB1, MAPK1, MAPK3, PDK1, PDK2, PTEN, PTK2, RBL2, SHC1, SOS1. BAD Phosphorylation and Anti-apoptotic Pathways: AKT1, BAD, GRB2, HRAS, IGF1R, IRS1, MAP2K1, MAPK1, MAPK3, RAF1, RPS6KA1, SHC1, SOS1, YWHAH. Genes Involved in the mTOR Signaling Pathway: AKT1, EIF4B, EIF4E, EIF4EBP1, EIF4G1, FKBP1A, MTOR, PDK1, PDK2, PTEN, RHEB, RPS6KB1, TSC1, TSC2. Regulation of eIF4e and p70 S6 Kinase: AKT1, EIF4E, EIF4EBP1 (4E-BP1), EIF4G1, MTOR, IRS1, MAPK1, MAPK14, MAPK3, PABPC1, PDK1, PDK2, PRKCA, PTEN, RPS6KB1. Other Genes Involved in the AKT Signaling Pathway: CASP9, CHUK, FOXO1, NFKBIA.
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文献和实验（GDC），其中固定的引物能特异性的检测非转录的基因组DNA重复片段，从而检测样品中是否存在DNA污染。H7到H9是三个重复的孔，均为反转录参照（RTC），用于检测RT反应的效率。H10到H12是阳性PCR参照（PPC），反映了PCR反应的效率。这些孔中加入了人工合成的DNA序列和相应的引物对。两组重复的对照RTC和PPC也可以用于检测芯片间和芯片内的一致性。 预设计的信号通路特异性PCR芯片 96孔模式的RT2Profiler PCR芯片根据SuperArray的Pathway-Centric
Wnt Signaling in the Early Sea Urchin Embryo
Wnt signaling regulates a remarkably diverse array of cellular and developmental events during animal embryogenesis and homeostasis. The crucial role that Wnt signaling plays in regulating axial patterning in early embryos
is made through the integration of the pathway of NF-κB activation with a complex array of cell signaling networks that are at present poorly understood. Here, two methods are presented, protein co-immunoprecipitation and subcellular co-localization by immunofluorescence
