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- 详细信息
- 文献和实验
- 技术资料
- 免疫原:
Purified recombinant fragment of SRA expressed in E. coli.
- 亚型:
Mouse IgG1
- 形态:
Each vial contains 0.1 ml ascitic fluid with 0.03% sodium azide.
- 保存条件:
Store at -20°C
- 克隆性:
单克隆
- 标记物:
见下方详细说明
- 适应物种:
H
- 保质期:
1-2年
- 抗原来源:
Purified recombinant fragment of SRA expressed in E. coli.
- 目录编号:
252655
- 级别:
超纯
- 库存:
大量
- 供应商:
Abbiotec
- 宿主:
Mouse
- 应用范围:
WB, IHC
- 浓度:
见详细说明信息
- 靶点:
SRA (1D4H)
- 抗体英文名:
SRA (1D4H) Antibody
- 抗体名:
SRA (1D4H) Antibody
- 规格:
0.1 ml
SRA (1D4H) Antibody产品详细介绍:
| 产品名称: | SRA (1D4H) Antibody |
| 说明书: | 【点击查看详细说明及参考图片】 |
| 货号: | 252655 |
| 规格: | 0.1 ml |
| 产品描述: | SRA (Steroid receptor RNA activator 1) is a 237-amino acid protein (~27kDa), belongs to the growing family of functional non-coding RNAs. SRA was originally described as the first functional noncoding RNA able to specifically coactivate the activity of steroid receptors. Specifically, SRA exists as both an RNA transcript that forms a complex with steroid receptor coactivator-1 and as a stably expressed protein. Its expression is strongly up-regulated in many human tumors of the breast, uterus and ovary, suggesting a potential role in pathogenesis. Although coactivation of steroid-dependent transcription by SRA is accompanied by a proliferative response, overexpression is not in itself sufficient to induce turmorigenesis. |
| 克隆类型: | Mouse Monoclonal Antibody |
| 亚型: | Mouse IgG1 |
| 免疫原: | Purified recombinant fragment of SRA expressed in E. coli. |
| 适用物种: | H |
| 应用范围: | WB, IHC |
| 应用说明: | WB: 1:500-1:2000; IHC: 1:200-1:1000; |
| 别名: | Steroid receptor RNA activator 1; Steroid receptor RNA activator protein; SRAP; SRA1 |
| 形态: | Each vial contains 0.1 ml ascitic fluid with 0.03% sodium azide. |
| 保存条件: | Store at 4°C for short term use only. Store at -20°C for storage over 1 month. Product is guaranteed 6 months from the date of shipment. |
| 参考文献: |
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文献和实验总蛋白(包括质膜和细胞器膜蛋白),但费时费力。目前,有一种最新型有效的膜蛋白提取工具,并具有高纯度、高特异性、高载量温和提取的优点。是基于1980年科学家在牛眼视网膜中发现的一种命名为Rho1D4的氨基酸序列以及其对应的抗体来作为亲和标签纯化膜蛋白取得了非常好的效果,将Rho1D4抗体链接在琼脂糖或磁珠上,用于亲和层析带有Rho1D4标签的膜蛋白,能近乎完美的解决这些研究难题。1) 什么是Rho1D4?Rho1D4是指在牛眼视网膜细胞内的牛视紫红质C端的最后九位氨基酸。Rho1D4得名于与该序列
Hydrophobic groups (疏水基团):排斥水分子,因此互相作用产生非水性环境。 Hyperchromicity (增色效应):当DNA 变性时吸光度增加的现象。 Hypervariable region (高度可变区):当不同抗体比较时表现出最大变化的区域。
Purification, Quantification, and Functional Analysis of Complement Factor H
Complement Factor H (FH) is an abundant, non-enzymic plasma/serum glycoprotein, which has a major role in regulating activation of the complement system. It can be purified from human plasma/serum by affinity chromatography, using
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