- ￥3000 - 3999
- Abbiotec
- 美国
- 254147
- 2025年07月10日
- E, WB
- Rabbit
- H, M, R
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- 详细信息
- 技术资料
- 免疫原：
KLH-conjugated synthetic peptide encompassing a sequence within human RWDD3.
- 亚型：
Rabbit Ig
- 形态：
Each vial contains 0.1 ml IgG in PBS pH 7.4 with 0.02% sodium azide. Antibody was purified by immunogen affinity chromatography.
- 保存条件：
Store at -20°C.
- 克隆性：
多克隆
- 标记物：
见下方详细说明
- 适应物种：
H, M, R
- 宿主：
Rabbit
- 应用范围：
E, WB
- 浓度：
见详细说明信息
- 靶点：
RWDD3
- 抗体英文名：
RWDD3 Antibody
- 抗体名：
RWDD3 Antibody
- 规格：
0.1 mg
RWDD3 Antibody产品详细介绍：
| 产品名称： | RWDD3 Antibody |
| 说明书： | 【点击查看详细说明及参考图片】 |
| 货号： | 254147 |
| 规格： | 0.1 mg |
| 产品描述： | RWDD3 (RSUME), a small RWD-containing protein, has a central role in sumoylation by enhancing SUMO conjugation in the regulatory network of immune–inflammatory signals. RWDD3 increases Ikappabeta sumoylation and stability. In addition, RWDD3 inhibits TNF-alpha-induced kappaB-LUC (Luciferase) reporter activity, showing the functional consequence of Ikappabeta increased stability. RSUME-enhanced sumoylation of Ikappabeta leads to the inhibition of NF-kappabeta activity on two well-known inflammatory genes, IL-8 and cyclooxygenase-2 (Cox-2) and therefore may also favor anti-inflammatory pathways. Expression of RWDD3 was induced under hypoxic conditions and it has a potential role during vascularization. Both BMP-4 and RWDD3 may be interesting targets for inhibiting steps involved in pituitary tumorigenesis. |
| 克隆类型： | Rabbit Polyclonal Antibody |
| 亚型： | Rabbit Ig |
| 免疫原： | KLH-conjugated synthetic peptide encompassing a sequence within human RWDD3. |
| 适用物种： | H, M, R |
| 应用范围： | E, WB |
| 应用说明： | E: 1:500-1:1,000; WB: 1:100-1:500 |
| 别名： | RWDD3 ; RWD domain containing 3; RSUME; RWD-containing sumoylation enhancer |
| 形态： | Each vial contains 0.1 ml IgG in PBS pH 7.4 with 0.02% sodium azide. Antibody was purified by immunogen affinity chromatography. |
| 保存条件： | Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment. |
| 参考文献： |
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RWDD3 Antibody
￥3000 - 3999
