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- 详细信息
- 文献和实验
- 技术资料
- 免疫原:
KLH-conjugated synthetic peptide encompassing a sequence within human PNAS4.
- 亚型:
Rabbit Ig
- 形态:
Each vial contains 0.1 ml IgG in PBS pH 7.4 with 0.02% sodium azide. Antibody was purified by immunogen affinity chromatography.
- 保存条件:
Store at -20°C.
- 克隆性:
多克隆
- 标记物:
见下方详细说明
- 适应物种:
H, M, R
- 宿主:
Rabbit
- 应用范围:
E, WB
- 浓度:
见详细说明信息
- 靶点:
PNAS4
- 抗体英文名:
PNAS4 Antibody
- 抗体名:
PNAS4 Antibody
- 规格:
0.1 mg
PNAS4 Antibody产品详细介绍:
| 产品名称: | PNAS4 Antibody |
| 说明书: | 【点击查看详细说明及参考图片】 |
| 货号: | 254087 |
| 规格: | 0.1 mg |
| 产品描述: | PNAS4 is a highly conserved protein that shares high homology from plants to animals. It was initially identified as a putative apoptosis-related protein in the human acute promyelocytic leukemia cell line NB4. PNAS4 is activated during the early response to DNA damage and can inhibit proliferation via apoptosis when overexpressed in some tumor cells such as U2OS, SKOV3, and A549. PNAS4 inhibits tumor cell proliferation through the following mechanisms: (i) overexpression of PNAS4 causes S phase arrest by regulating the expression of cell cycle-related proteins and (ii) PNAS4 induces apoptosis through the mitochondrial apoptosis pathway. Recent evidence has shown that PNAS4 may be involved in the genesis of some cancers and could be a potential candidate for lung cancer therapy alone or in combination with gemcitabine. At least two isoforms of PNAS4 are known to exist. |
| 克隆类型: | Rabbit Polyclonal Antibody |
| 亚型: | Rabbit Ig |
| 免疫原: | KLH-conjugated synthetic peptide encompassing a sequence within human PNAS4. |
| 适用物种: | H, M, R |
| 应用范围: | E, WB |
| 应用说明: | E: 1:500-1:1,000; WB: 1:100-1:500 |
| 别名: | PNAS4; PPPDE peptidase domain containing 1; CGI-146; FAM152A |
| 形态: | Each vial contains 0.1 ml IgG in PBS pH 7.4 with 0.02% sodium azide. Antibody was purified by immunogen affinity chromatography. |
| 保存条件: | Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment. |
| 参考文献: |
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