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PARL Antibody

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  • ¥3000 - 3999
  • Abbiotec已认证
  • 美国
  • 253929
  • 2025年07月10日
  • E, WB, ICC
  • Rabbit
  • H, M, R
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    • 详细信息
    • 文献和实验
    • 技术资料
    • 免疫原

      KLH-conjugated synthetic peptide encompassing a sequence within human PARL.

    • 亚型

      Rabbit Ig

    • 形态

      Each vial contains 0.1 ml IgG in PBS pH 7.4 with 0.02% sodium azide. Antibody was purified by immunogen affinity chromatography.

    • 保存条件

      Store at -20°C.

    • 克隆性

      多克隆

    • 标记物

      见下方详细说明

    • 适应物种

      H, M, R

    • 宿主

      Rabbit

    • 应用范围

      E, WB, ICC

    • 浓度

      见详细说明信息

    • 靶点

      PARL

    • 抗体英文名

      PARL Antibody

    • 抗体名

      PARL Antibody

    • 规格

      0.1 mg

    产品细节图片1
    PARL Antibody产品详细介绍:
    产品名称: PARL Antibody
    说明书: 点击查看详细说明及参考图片
    货号: 253929
    规格: 0.1 mg
    产品描述: PARL is a mitochondrial integral membrane protein and a member of the highly conserved rhomboid superfamily of membrane proteins. PARL is required for the control of apoptosis during postnatal growth and is required for the processing of OPA1, a protein that prevents the release of cytochrome C from the mitochondria in response to apoptotic signals. In lymphocytes and neurons, PARL’s association with other proteins, such as the Bcl-2 family-related protein Hax1 and Omi can lead to the proteolytic processing of Omi by PARL, preventing the accumulation of Bax, thereby suppressing apoptosis. Variations in this gene have been associated with increased risk for type 2 diabetes. PARL may also play a role in the progression of Alzheimer’s disease through its associations with presenilin-1 and -2. Despite its predicted molecular weight of ~42kDa, PARL is observed at a higher molecular weight in SDS-PAGE. Multiple isoforms of PARL are known to exist.
    克隆类型: Rabbit Polyclonal Antibody
    亚型: Rabbit Ig
    免疫原: KLH-conjugated synthetic peptide encompassing a sequence within human PARL.
    适用物种: H, M, R
    应用范围: E, WB, ICC
    应用说明: E: 1:500-1:1,000; WB: 1:100-1:500; ICC: 1:100-1:500
    别名: PARL; Presenilin-associated rhomboid-like protein; PSARL; PSARL1; PSNENIP2
    形态: Each vial contains 0.1 ml IgG in PBS pH 7.4 with 0.02% sodium azide. Antibody was purified by immunogen affinity chromatography.
    保存条件: Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment.
    参考文献:

    ABBIOTEC产品提供质量保证,提供完善的售后和技术支持,ABBIOTEC产品正品包装:
    产品细节图片2 产品细节图片3

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    图标文献和实验
    相关实验
    • Generation of Antibody Molecules Through Antibody Engineering

      been overcome to a large extent using genetic-engineering techniques to produce chimeric mouse/human and completely human antibodies. Such an approach is particularly suitable because of the domain structure of the antibody molecule ( 2 ), where functional

    • The Antibody Molecule

      The importance of antibody molecules was first recognized in the 1890s, when it was shown that immunity to tetanus and diphtheria was caused by antibodies against the bacterial exotoxins (1 ). Around the same time, it was shown that antisera

    • Antibody Storage

        General comments: Antibodies, like most proteins, do not like to be freeze-thawed. Avoid repetitive freezing of your solution. The best way to store your antibody is to keep a high protein concentration (>1 mg/ml), add some protease

    图标技术资料

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