NPAS3 Antibody_NPAS3抗体

NPAS3 Antibody_NPAS3抗体

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  • ¥3000 - 3999
  • Abbiotec已认证
  • 美国
  • 2025年07月16日
  • E, WB, IHC
  • Rabbit
  • H, M, R
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    • 详细信息
    • 技术资料
    • 免疫原

      KLH-conjugated synthetic peptide encompassing a sequence within human NPAS3.

    • 亚型

      Rabbit Ig

    • 形态

      Each vial contains 0.1 ml IgG in PBS pH 7.4 with 0.02% sodium azide. Antibody was purified by immunogen affinity chromatography.

    • 保存条件

      Store at -20°C.

    • 克隆性

      多克隆

    • 标记物

      见下方详细说明

    • 适应物种

      H, M, R

    • 保质期

      1-2年

    • 抗原来源

      KLH-conjugated synthetic peptide encompassing a sequence within human NPAS3.

    • 目录编号

      253716

    • 级别

      超纯

    • 库存

      大量

    • 供应商

      Abbiotec

    • 宿主

      Rabbit

    • 应用范围

      E, WB, IHC

    • 浓度

      见详细说明信息

    • 靶点

      NPAS3

    • 抗体英文名

      NPAS3 Antibody

    • 抗体名

      NPAS3 Antibody

    • 规格

      0.1 mg

    NPAS3 Antibody_NPAS3抗体
    NPAS3 Antibody产品详细介绍:
    产品名称: NPAS3 Antibody
    说明书: 点击查看详细说明及参考图片
    货号: 253716
    规格: 0.1 mg
    产品描述: Neuronal PAS domain protein 3 (NPAS3) is a brain-enriched basic helix-loop-helix PAS domain transcription factor and is broadly expressed in the developing neuroepithelium and has recently found to be disrupted by genetic translocation in a family affected with schizophrenia. It was recently shown to be involved in the regulation of FGF signaling in the dentate gyrus by controlling the expression of the FGF receptor subtype 1 and in turn neurogenesis emanating from this region. NPAS3-null mice were growth-retarded and displayed brain defects that included reduced size of the anterior hippocampus, hypoplasia of the corpus callosum, and enlargement of the ventricles, as well as several behavioral abnormalities. Furthermore, these NPAS3-null mice also exhibited disruptions in several neurosignaling pathways involving glutamate, dopamine, and serotonin. These results demonstrate the essential role played by NPAS3 during structural and functional brain development. At least three isoforms of NPAS3 are known to exist.
    克隆类型: Rabbit Polyclonal Antibody
    亚型: Rabbit Ig
    免疫原: KLH-conjugated synthetic peptide encompassing a sequence within human NPAS3.
    适用物种: H, M, R
    应用范围: E, WB, IHC
    应用说明: E: 1:500-1:1,000; WB: 1:100-1:500; IHC: 1:100-1:500
    别名: NPAS3 ; Neuronal PAS domain-containing protein 3; member of Pas protein 6; MOP6
    形态: Each vial contains 0.1 ml IgG in PBS pH 7.4 with 0.02% sodium azide. Antibody was purified by immunogen affinity chromatography.
    保存条件: Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment.
    参考文献:

    ABBIOTEC产品提供质量保证,提供完善的售后和技术支持,ABBIOTEC产品正品包装:
    NPAS3 Antibody_NPAS3抗体 NPAS3 Antibody_NPAS3抗体

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