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- 详细信息
- 文献和实验
- 技术资料
- 免疫原:
KLH-conjugated synthetic peptide encompassing a sequence within mouse norepinephrine transporter.
- 亚型:
Mouse IgG1
- 形态:
Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of HEPES (pH7.5), 0.01% BSA, with 50% glycerol. Antibody was purified by Protein-G affinity chromatography.
- 保存条件:
Store at -20°C.
- 克隆性:
单克隆
- 标记物:
见下方详细说明
- 适应物种:
M, R
- 保质期:
1-2年
- 抗原来源:
KLH-conjugated synthetic peptide encompassing a sequence within mouse norepinephrine transporter.
- 目录编号:
253181
- 级别:
超纯
- 库存:
大量
- 供应商:
Abbiotec
- 宿主:
Mouse
- 应用范围:
E, WB
- 浓度:
见详细说明信息
- 靶点:
Norepinephrine Transporter
- 抗体英文名:
Norepinephrine Transporter Antibody
- 抗体名:
Norepinephrine Transporter Antibody
- 规格:
0.1 ml
Norepinephrine Transporter Antibody产品详细介绍:
| 产品名称: | Norepinephrine Transporter Antibody |
| 说明书: | 【点击查看详细说明及参考图片】 |
| 货号: | 253181 |
| 规格: | 0.1 ml |
| 产品描述: | Norepinephrine Transporter [NET] (or noradrenaline transporter (NAT)) is a monoamine transporter that transports the neurotransmitter noradrenaline from the synapse back to its vesicles for storage until later use. It also appears to transport the neurotransmitter dopamine in the same way, but to a lesser degree. Studies have shown a decrease in NET levels in the locus coeruleus in patients diagnosed with major depression. Cocaine, amphetamines and many therapeutic antidepressants, such as the SNRIs (Serotonin-norepinephrine reuptake inhibitors) and the tricyclic antidepressants (TCAs) act to raise noradrenaline. Furthermore, deficits in the NET gene have been associated with ADHD. |
| 克隆类型: | Mouse Monoclonal Antibody |
| 亚型: | Mouse IgG1 |
| 免疫原: | KLH-conjugated synthetic peptide encompassing a sequence within mouse norepinephrine transporter. |
| 适用物种: | M, R |
| 应用范围: | E, WB |
| 应用说明: | E: 1:500-1:1,000; WB: 1:2,000 |
| 别名: | Sodium-dependent noradrenaline transporter; Norepinephrine transporter; NET Solute carrier family 6 member 2 |
| 形态: | Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of HEPES (pH7.5), 0.01% BSA, with 50% glycerol. Antibody was purified by Protein-G affinity chromatography. |
| 保存条件: | Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment. |
| 参考文献: |
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文献和实验Transporter Current Measurements
Na+ /K+ pump, Na+ /Ca2+ exchanger, glutamate transporter and other transporters for dopamine, norepinephrine, GABA, and others, are all electrogenic. These transporters or exchanger transport Na+ ions, with or without transmitters
alleles (homozygote). This procedure has been used to generate animals lacking either the plasma membrane dopamine transporter (DAT; Fig. 2 ) or the vesicular monoamine transporter (VMAT2; Fig. 3 ). Both DAT and VMAT2 are essential for dopamine homeostasis
The IUBMB-Endorsed Transporter Classification System
Transport systems are essential to every living cell. They (1) allow the entry of all essential nutrients into the cell and its compartments, (2) regulate the cytoplasmic concentrations of metabolites by excretion mechanisms, (3) provide
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