- ￥3000 - 3999
- Abbiotec
- 美国
- 253982
- 2025年07月14日
- E, WB, IHC
- Rabbit
- H, M, R
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- 详细信息
- 文献和实验
- 技术资料
- 免疫原：
KLH-conjugated synthetic peptide encompassing a sequence within human JPH3.
- 亚型：
Rabbit Ig
- 形态：
Each vial contains 0.1 ml IgG in PBS pH 7.4 with 0.02% sodium azide. Antibody was purified by immunogen affinity chromatography.
- 保存条件：
Store at -20°C.
- 克隆性：
多克隆
- 标记物：
见下方详细说明
- 适应物种：
H, M, R
- 宿主：
Rabbit
- 应用范围：
E, WB, IHC
- 浓度：
见详细说明信息
- 靶点：
JPH3
- 抗体英文名：
JPH3 Antibody
- 抗体名：
JPH3 Antibody
- 规格：
0.1 mg
JPH3 Antibody产品详细介绍：
| 产品名称： | JPH3 Antibody |
| 说明书： | 【点击查看详细说明及参考图片】 |
| 货号： | 253982 |
| 规格： | 0.1 mg |
| 产品描述： | Junctional complexes between the plasma membrane (PM) and endoplasmic/sarcoplasmic reticulum (ER/SR) are a common feature of all excitable cell types and mediate cross talk between cell surface and intracellular ion channels. Junctophilins (JPs) are important components of the junctional complexes. JPs are composed of a carboxy-terminal hydrophobic segment spanning the ER/SR membrane and a remaining cytoplasmic domain that shows specific affinity for the PM. Four JPs have been identified as tissue-specific subtypes derived from different genes: JPH1 is expressed in skeletal muscle, JPH2 is detected throughout all muscle cell types, and JPH3 and JPH4 are predominantly expressed in the brain. In the CNS, both JPH3 and JPH4 are expressed throughout neural sites and contribute to the subsurface cistern formation in neurons. Mice lacking both JPH3 and JPH4 subtypes exhibit serious symptoms such as impaired learning and memory and are accompanied by abnormal nervous functions. A repeat expansion in JPH3 is associated with Huntington disease-like 2. At least two isoforms of JPH3 are known to exist. |
| 克隆类型： | Rabbit Polyclonal Antibody |
| 亚型： | Rabbit Ig |
| 免疫原： | KLH-conjugated synthetic peptide encompassing a sequence within human JPH3. |
| 适用物种： | H, M, R |
| 应用范围： | E, WB, IHC |
| 应用说明： | E: 1:500-1:1,000; WB: 1:100-1:500; IHC: 1:100-1:500 |
| 别名： | JPH3 ; Junctophilin 3; JP3; JP-3; TNRC22; HDL2 |
| 形态： | Each vial contains 0.1 ml IgG in PBS pH 7.4 with 0.02% sodium azide. Antibody was purified by immunogen affinity chromatography. |
| 保存条件： | Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment. |
| 参考文献： |
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文献和实验Generation of Antibody Molecules Through Antibody Engineering
been overcome to a large extent using genetic-engineering techniques to produce chimeric mouse/human and completely human antibodies. Such an approach is particularly suitable because of the domain structure of the antibody molecule ( 2 ), where functional
The importance of antibody molecules was first recognized in the 1890s, when it was shown that immunity to tetanus and diphtheria was caused by antibodies against the bacterial exotoxins (1 ). Around the same time, it was shown that antisera
General comments: Antibodies, like most proteins, do not like to be freeze-thawed. Avoid repetitive freezing of your solution. The best way to store your antibody is to keep a high protein concentration (>1 mg/ml), add some protease
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