- ￥3000 - 3999
- Abbiotec
- 美国
- 253817
- 2025年07月08日
- E, WB, ICC
- Rabbit
- H
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- 详细信息
- 文献和实验
- 技术资料
- 免疫原：
KLH-conjugated synthetic peptide encompassing a sequence within human CXCR4-Lo.
- 亚型：
Rabbit Ig
- 形态：
Each vial contains 0.1 ml IgG in PBS pH 7.4 with 0.02% sodium azide. Antibody was purified by ion exchange chromatography.
- 保存条件：
Store at -20°C.
- 克隆性：
多克隆
- 标记物：
见下方详细说明
- 适应物种：
H
- 宿主：
Rabbit
- 应用范围：
E, WB, ICC
- 浓度：
见详细说明信息
- 靶点：
CXCR4-Lo
- 抗体英文名：
CXCR4-Lo Antibody
- 抗体名：
CXCR4-Lo Antibody
- 规格：
0.1 mg
CXCR4-Lo Antibody产品详细介绍：
| 产品名称： | CXCR4-Lo Antibody |
| 说明书： | 【点击查看详细说明及参考图片】 |
| 货号： | 253817 |
| 规格： | 0.1 mg |
| 产品描述： | Human immunodeficiency virus (HIV) and related viruses require coreceptors, in addition to CD4, to infect target cells. Some G protein-coupled receptors including CCR5, CXCR4, CCR3, CCR2b and CCR8 in the chemokine receptor family, and four new human molecules GPR15, STRL33, GPR1 and V28 were recently identified as HIV coreceptors. Among them, CXCR4 is a principal coreceptor for T-cell tropic strains of HIV-1 fusion and entry of human white blood cells. CXCR4 is also required for the infection by dual-tropic strains of HIV-1 and mediates CD-4 independent infection by HIV-2. The alpha-chemokine SDF-1 is the ligand for CXCR4 and prevents infection by T-tropic HIV-1. CXCR4 associates with the surface CD4-gp120 complex before HIV enters target cells. CXCR4 messenger RNA levels correlated with HIV-1 permissiveness in diverse human cell types. Antibodies to CXCR4 block HIV-1 and HIV-2 fusion and infection of human target cells. The amino-terminal domain and the second extracellular loop of CXCR4 serve as HIV binding sites. This antibody is specific for the longer isoform of CXCR4. |
| 克隆类型： | Rabbit Polyclonal Antibody |
| 亚型： | Rabbit Ig |
| 免疫原： | KLH-conjugated synthetic peptide encompassing a sequence within human CXCR4-Lo. |
| 适用物种： | H |
| 应用范围： | E, WB, ICC |
| 应用说明： | E: 1:500-1:1,000; WB: 1:100-1:500; ICC: 1:100-1:500 |
| 别名： | CXCR4-Lo; Fusin; LESTR; HUMSTR |
| 形态： | Each vial contains 0.1 ml IgG in PBS pH 7.4 with 0.02% sodium azide. Antibody was purified by ion exchange chromatography. |
| 保存条件： | Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment. |
| 参考文献： |
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文献和实验CXCR4, the receptor for stromal cell-derived factor (SDF)-1, was expressed in Saccharomyces cerevisiae coupled to the pheromone response pathway via a chimeric Gα subunit. Engagement of CXCR4 by SDF-1 resulted in expression of reporter genes
飞蝗locust，flying locust，migratory lo cust
大陆广阔的草原地区，飞蝗屡次大规模发生，结成遮天盖日的大蝗群，集群迁飞。被侵入的地区，农作物时常遭到毁灭性的灾害。旧大陆广泛分布的飞蝗（ Lo- custa migratoria），高加索、地中海地区的Doci- staurus marrocanus，非洲沙漠地区的Schistocercagregaria，南非洲的Locustana pardalina，南美洲的S.paranensis，北美洲的Melanoplus spretus是其代表种，飞蝗正是这些蝗虫种类的群居型。
博塔洛氏管 Botal（ lo）′ s duct 亦称博塔洛氏动脉管。是以巴黎医生博塔洛（ L． Botallo， 1530）的名字命名的。在肺鱼类和有肺的高等脊椎动物发生时，由于咽部腹侧第四鳃弓相应的第四动脉弓发展为肺动脉，但在两栖类的有尾类，则由第四动脉弓的下部向肺分化成肺动脉，其余的部分形成小管与背大动脉相连，这个小管称博塔洛氏管。羊膜炎在胚胎期、胎儿期有此结构，第四动脉弓血液的一部分，由肺动脉送到肺以营养之，但由于呼吸是尿囊膜进行的，血液的大部分是经博塔洛氏管导入背大动脉．
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